Multicenter Observational Study on the Prevalence of Inappropriate Prescribing in Elderly Patients At Admission and Discharge from a Hospital Ward Using the STOPP/START Criteria
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Prevalence of inappropriate prescribing in elderly patients at admission to an acute care hospital using STOPP/START criteria
研究概览
简要总结
The management of pharmacotherapy in elderly patients is an increasingly critical aspect, as polypharmacy, combined with the pharmacokinetic and pharmacodynamic changes typical of aging, makes older adults more sensitive to the development of adverse reactions. This highlights the importance of appropriate use of pharmacotherapy that considers the risks and benefits of individual treatments. The aim of this study is to measure the prevalence of pharmacological appropriateness using the STOPP/START criteria (version 2) at admission and discharge from an acute geriatric ward, thereby evaluating the impact of hospitalization on medication prescribing.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 70 Years 至 —（Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients aged ≥ 70 years admitted to a geriatric ward
- •Regardless of ethnicity, gender, or type of illness
- •Patients transferred from another ward
- •Patients admitted to another ward for support
排除标准
- •Patients in the terminal phase (<6 months life expectancy)
- •Criteria for exit from the study (Dropout):
- •Patients transferred to another hospital ward
- •Patients who have deceased
结局指标
主要结局
Prevalence of inappropriate prescribing in elderly patients at admission to an acute care hospital using STOPP/START criteria
时间窗: Data collected at time Day 0 is analyzed by day 4. Data collected at time Day 1 is analyzed by day 4
The analysis of inappropriate prescriptions at admission "Day 0" will be evaluated as a single outcome measure by aggregating data using the STOPP/START criteria. Specific assessments will be reported separately, as they involve different types of information and units of measure: * Prevalence of inappropriate prescriptions: The proportion of patients with prescriptions deviating from STOPP/START criteria (%). * Characteristics of patient history: Data such as active and passive diseases (count), place of origin (categorical variable), reason for admission (categorical variable), and presence of ADL support (binary variable: Yes/No). * Clinical indicators: Charlson Comorbidity Index (numerical score), number of medications (count), presence of geriatric syndromes (binary variable: Yes/No). * Mobility status: Whether the patient is bedridden or ambulatory (categorical variable). * Hospitalization history: Number of admissions in the past year (count).
次要结局
- Prevalence of inappropriate prescribing in elderly patients at discharge from an acute care hospital using STOPP/START criteria.(Data collected at time Day 0 is analyzed by day 4. Data collected at time Day 1 is analyzed by day 4)
- Percentage of cases in which inappropriate prescribing will be detected at admission and discharge(Data collected at time Day 0 is analyzed by day 4. Data collected at time Day 1 is analyzed by day 4)
- Association between the prevalence of inappropriate prescriptions and clinical variables, measured using univariate and multivariate regression.(Data collected at time Day 0 is analyzed by day 4. Data collected at time Day 1 is analyzed by day 4)
研究者
Luca Pellizzari
Specialist in Geriatrics
Azienda Ospedaliera Universitaria Integrata Verona