Effect of Dexmedetomidine on QT Interval in Pediatric Patients Under General Anesthesia
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- Change in QT interval
研究概览
简要总结
Various medications used in anesthesia have been implicated in the prolongation of QT interval. Recently, there has been an increase in the use of dexmedetomidine in patients presenting for surgeries given its beneficial sedative, anxiolytic, and analgesic properties. It has several desirable properties including minimal respiratory side effects as well as the ability to decrease intraoperative and postoperative analgesic requirements. In many of the patients who present for routine surgical procedures, dexmedetomidine is a common component of their anesthetic care. This is a study to assess the effects of dexmedetomidine on the QT interval in children presenting for surgery.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •ASA grade 1 or
- •Scheduled to receive dexmedetomidine.
排除标准
- •Known allergy to dexmedetomidine.
结局指标
主要结局
Change in QT interval
时间窗: Baseline, 5 mins., 10 mins.
ECG will be done to assess QT interval prior to induction (baseline), after induction (5 mins.) and after dexmedetomidine (10 mins.)
次要结局
未报告次要终点
研究者
Senthil G. Krishna
Assistant Clinical Professor
Nationwide Children's Hospital
