NCT00219271已完成4 期
Effect Of Zoledronic Acid On Circulating And Bone Marrow-Residing Prostate Cancer Cells In Patients With Clinically Localized Prostate Cancer
适应症
干预措施
相关药物
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- To assess the activity of one year treatment with zoledronic acid
研究概览
简要总结
The objective of this study is to assess the effect Of zoledronic acid on circulating and bone marrow-residing prostate cancer cells in patients with clinically localized prostate cancer
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- 未提供
研究组 & 干预措施
Zoledronic acid
Experimental
4 mg IV infused over 15 minutes every 3 months
干预措施: Zoledronic acid (Drug)
结局指标
主要结局
To assess the activity of one year treatment with zoledronic acid
时间窗: 12 mos
次要结局
- Three-year disease free survival(3 years)
- Change in bone mineral density at 12, 24 and 36 months versus baseline(12, 24 and 36 months)
- Changes in bone resorption markers at 12, 24 and 36 months versus baseline(12, 24 and 36 months)
- Safety and tolerability through abnormal values and AE reporting(upto 36 mos)
研究者
研究点 (1)
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