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临床试验/NCT03037216
NCT03037216已完成不适用

Investigation of Exercise Training-Induced Myokines and Adipolkines in Humans

Joslin Diabetes Center2 个研究点 分布在 1 个国家目标入组 10 人开始时间: 2016年12月15日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
10
试验地点
2
主要终点
Changes in circulating proteins in the blood.

研究概览

简要总结

The purpose of this study is to find out whether exercise training leads to changes in the blood that are produced by exercised muscles and if these changes produce new hormones that affect the body's regulation of sugar and body weight.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Basic Science
盲法
None

入排标准

年龄范围
18 Years 至 50 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Age between 18-
  • Body mass index (BMI) must be ≥18.5 and ≤27 kg/m
  • HbA1c values ≤5.7%

排除标准

  • Age <18 and >50
  • HbA1c ≥ 5.7%; heart or lung disease
  • acute systemic infection accompanied by fever, body aches, or swollen lymph glands
  • BMI > 27 kg/m2
  • current dieting or weight loss efforts
  • current pregnancy or breastfeeding
  • known history of HIV/AIDS; cancer
  • biochemical evidence of renal or hepatic dysfunction; renal or liver disease demyelinating diseases such as multiple sclerosis or amyotrophic lateral sclerosis
  • recent blood donation
  • clinical history of stroke
  • hypertension (systolic > 140 mmHg or diastolic > 90 mmHg)
  • type 1 or 2 diabetes; inability to exercise at 50% of predicted heart rate (HR) reserve at baseline
  • Participants taking beta-blockers Participants who screen positive for The American Heart Association's contraindications to exercise testing

结局指标

主要结局

Changes in circulating proteins in the blood.

时间窗: Baseline vs. Post 10 Week Training.

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

研究点 (2)

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