Specific Language Impairment (SLI) in Children May Caused by Epileptic Brain Activity
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 160
- 试验地点
- 1
- 主要终点
- EEGs finding
研究概览
简要总结
The objective of this study was to find if there is a possible association and the impact of epilepsy and epileptiform activity in children with SLI.
详细描述
This study concentrates on the impact of epileptiform activity for childhood epilepsy on the speech and language disturbances in addition to the associated social, cognitive and intellectual dysfunctions.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 3 Years 至 6 Years（Child）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •80 children were suffering from specific language impairment
- •80 healthy children with age and sex match control group.
排除标准
- •Previous history of perinatal hypoxic-ischemic damage
- •meningitis or encephalitis
- •motor weakness
- •hearing disorders
- •IQ below seventy
- •CP, social deprivation
- •autism and
- •psychiatric disorders .
结局指标
主要结局
EEGs finding
时间窗: 24-48 hours
EEGs finding were defined according to the followings "Normal: within the range of frequency and amplitude distribution." "Epileptiform: Describes transient background activity with a characteristic spikes, sharp waves, spike-slow wave or sharp-slow wave complexes of focal or generalized distribution". "Abnormal non-epileptiform: deviations from normal in terms of background frequency patterns, usually in the form of excessive slow activity".
次要结局
未报告次要终点
研究者
Ahmed Esmael
Assistant Prof of Neurology
Mansoura University Hospital