跳至主要内容
临床试验/NCT06076278
NCT06076278招募中不适用

Effects of Home Based Resistance Training as Compared to Supervised Resistance Training Exercise in the Management of Osteoarthritis.

Foundation University Islamabad2 个研究点 分布在 1 个国家目标入组 34 人开始时间: 2023年8月30日最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
入组人数
34
试验地点
2
主要终点
Gait Stride length

研究概览

简要总结

Knee osteoarthritis is a degenerative pathology that is characterized by structural changes in the joint, such as joint space narrowing, thickening of the joint capsule, and cartilage degeneration that encourages friction between the bone surfaces and causes pain, which is thought to be a major symptom of knee osteoarthritis. Knee osteoarthritis (OA) treatment focuses on reducing pain while also enhancing function and quality of life by resistant training and Home-based exercise, a time-effective and practical treatment option for people with chronic conditions. As the past literature states that home based trainings are cost and time effective, However there is deficient evidence regarding effectiveness of home based strength training in case of knee osteoarthritis. More evidence is therefore needed in this regard.

详细描述

As the investigators know knee osteoarthritis (KOA) is common in elderly people, causes pain, loss of physical functioning, and disability. Knee osteoarthritis (OA) treatment focuses on reducing pain while also enhancing function and quality of life. Increased interest in non-pharmacologic treatments for OA is a result of declining enthusiasm for cyclooxygenase-2 inhibitors as a means of treating knee OA pain and failing clinical trials of OA medications that aim to change the illness. The two hallmarks of non-pharmacologic treatment are resistance training (RT) exercise programs and educational self-management (SM) programs and It has been evident in recent years that RT can have a favorable impact on activity-related energy expenditure, total free-living energy expenditure, and resting energy expenditure (REE) (AEE).Home based training; Home-based exercise, a time-effective and practical treatment option for people with chronic conditions like KOA, is becoming more valued by rehabilitation professionals and researchers. It can performed by patients individually at home, The goal of home-based and hospital-based exercise is the same; that is, to relieve pain and improve function by strengthening lower limb muscles, improving neuromuscular control, and range of joint motion in the affected knees. The main aim of the study is to determine the effectiveness of home-based resistance training as compared to supervised resistance training exercises in the management of knee osteoarthritis in terms of pain, ROM , disability, muscle strength and spatiotemporal parameter of gait. The participants meeting the eligibility criteria will be recruited, followed by random allocation to 2 groups. Both groups will receive standard treatment protocol which consists resistant training .12 sessions will be provided on alternative days. Pre and Post assessment of will be noted .

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Prevention
盲法
None

入排标准

年龄范围
25 Years 至 65 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Adults aged 25 to 60 years experiencing knee pain.
  • Both male and female.
  • Patients with grade 1 to 3 OA based on Kellgren Lawrence classification of knee OA.
  • Those participants with 4-8 on NPRS

排除标准

  • Individuals with serious pathology such as malignancy, inflammatory disorder or infection.
  • Individual with history of knee surgery or replacement.
  • Those patients who have received physiotherapy from last 2 months.
  • Those patients who have received any surgical treatment for SIJ dysfunction

结局指标

主要结局

Gait Stride length

时间窗: 4 weeks

Stride length (m) = speed (m/s) x cycle time (s)

Pain severity

时间窗: 4 week

Pain will be measured using the Numeric Pain Rating Scale, which is an 11-item scale.The higher the score the greater will be pain severity

Disability level of participant

时间窗: 4 weeks

Disability will be assessed using Western Ontario and McMaster University Osteoarthritis Index. The scores for each subscale are summed up, with a possible score range of 0-20 for Pain, 0-8 for Stiffness, and 0-68 for Physical Function. Usually a sum of the scores for all three subscales gives a total WOMAC score. Higher scores on the WOMAC indicate worse pain, stiffness, and functional limitations

Muscle strength

时间窗: 4 weeks

measured by using Modified Sphygmomanometer Dynamometry

Gait Cadence

时间窗: 4 weeks

Cadence (steps/min) = steps counted x 60/time (s)

Gait Speed

时间窗: 4 weeks

Gait Speed (m/s) = distance (m) / time (s)

Range of motion

时间窗: 4 weeks

Description measured by using Goniometer

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

研究点 (2)

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