Association of Cognition With Functional Mobility in People With Alzheimer's Disease
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 64
- 试验地点
- 1
- 主要终点
- Montreal Cognitive Assesment (MoCA)
研究概览
简要总结
This study aimed to investigate relationship between cognitive function and functional mobility in Alzheimer's disease.
详细描述
Our hypothesis is that the decrease in cognitive function in individuals with Alzheimer's disease is associated with the level of functional mobility. Sociodemographic information of participants will be recorded. Cognition will assessed with Montreal Cognitive Assessment (MoCA), global score and MoCA's visuospatial executive functions, naming, attention, language, abstract thinking, delayed recall, orientation sub-scores will recorded. Functional mobility will assessed Timed Up and Go Test and 5 Times Sit&Stand Test.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Diagnosed with Alzheimer's disease according to the National Institute of --Neurological and Communicative Disorders and Stroke and the Alzheimer's Disease (NINCDS-ADRDA) criteria,
- •Over 65 years old,
- •Cases who could understand the instructions given in Turkish were included in the study,
- •Having ambulation skill independently or with walking aid.
排除标准
- •Dementia with Lewy bodies, frontotemporal dementia and one of the other types of dementia,
- •Having a pulmonary, neurological, musculoskeletal or rheumatological disease that may prevent exercise,
- •Unstable medical condition (uncontrolled diabetes or hypertension, deep vein thrombosis, etc.),
- •Subjects with visual or auditory deficits or behavioral problems that would make communication difficult were not included in the study.
结局指标
主要结局
Montreal Cognitive Assesment (MoCA)
时间窗: Baseline
MoCA assesses cognitive skills such as visuospatial / executive functioning, object naming, memory, attention, language, abstraction, orientation. Higher scores reflect the better performance.
Timed Up and Go Test
时间窗: Baseline
Timed Up and Go Test measures the level of functional mobility skills and, assess fall risk and balance. The time elapsed between standing up from the sitting position, walking the distance of 3 meters, coming back and sitting back on the chair is recorded. The shorter time reflect the better performance.
5 Time Sit to Stand Test
时间窗: Baseline
5 Time Sit to Stand Test measures the level of functional mobility skills and, assess fall risk and lower extremity strength. The test measures the time taken to stand five times from a sitting position as quickly as possible. The shorter time reflect the better performance.
次要结局
未报告次要终点
研究者
Kübra Nur Menengiç
Student of PhD
Istanbul University - Cerrahpasa (IUC)