NCT04027127已完成不适用
The Effect of Serum Netrin-1 Levels on Diagnosis and Prognosis in Patients Presenting to the Emergency Department With Acute Coronary Syndrome
Aksaray University Training and Research Hospital0 个研究点目标入组 238 人开始时间: 2013年9月15日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 238
- 主要终点
- serum netrin-1 value
研究概览
简要总结
In our study, Netrin -1; We found that patients with ACS increased at the time of admission, decreased TIMI 3 flow after angiography, and higher risk groups in high risk groups such as TIMI and GRACE were found to have higher Netrin-1 levels.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- Single (Participant)
盲法说明
Patient group; Those diagnosed with ACS over 18 years of age, planned angiography and accepted angiography. The control group consisted of volunteers without disease.
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patients over the age of 18
- •diagnose ACS
- •patients undergoing angiography
排除标准
- •CVE history
- •Neurological disease
- •Pregnancy and Lactation
- •Liver failure
- •Diagnosed malignity
- •Use of anticonvulsant and nephrotoxic medication
- •Chronic kidney disease
- •Not having angiography
- •Developing acute renal failure after angiography
- •Patients who rejected to participate were excluded.
结局指标
主要结局
serum netrin-1 value
时间窗: 30 minute
Netrin-1 in plasma was measured by enzyme-linked immunosorbent assay (ELISA) (Mybıosource MBS044526 ) All assays were performed in duplicate. Plasma Netrin-1 is expressed in picograms (pg) per mg.
次要结局
未报告次要终点
研究者
huseyin mutlu
Asst. Prof. Dr. Principal Investigator
Aksaray University Training and Research Hospital
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