Internal Jugular Vein Distensibility and Pleth Variability Index for Evaluating Fluid Responsiveness
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- number of patients with significant change in VJI distensibility and pleth variebility index
研究概览
简要总结
Assessment of intravascular volume status is crucial in order to predict the efficacy of volume status in major abdominal surgery. The aim of the study is to verify the feasibility and usefulness of the internal jugular vein distensibility index as an adjunct to the pleth variebility index(PVI) to predict fluid responsiveness in major abdominal surgery.
详细描述
Forty patients above age 18 and ASA status I-III who are undergoing major abdominal surgery will be enrolled in the study. patients with right heart failure, arrythmia, severe valve stenosis or regurgitation will be excluded. After induction of general anesthesia, when the patients are hemodynamically stabilised, PVI and jugular vein distensibility will be calculated and recorded. after volume load with 500 ml gel infusion(in 15 min), measurements will be repeated within 10 minutes and recorded. Patients will be allocated to 2 groups according to the change in mean arterial pressure(MAP) after volume expansion: Responders will be defined as an increase in MAP by >%10; while nonresponders will be defined as an increase in MAP <%10 or decrease in MAP.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •American Society of Anesthesiologists(ASA) physical status I-III patients
- •patients undergoing major abdominal surgery
排除标准
- •arrythmia
- •severe right ventricle failure
结局指标
主要结局
number of patients with significant change in VJI distensibility and pleth variebility index
时间窗: during surgery at day 0
volume responders with significant change in jugular vein distensibility and pleth variebility index
次要结局
未报告次要终点
研究者
MELTEM CAKMAK
Anesthesiologist
Tepecik Training and Research Hospital