Changes in meibomian gland structure and function in adults suffering from dry eye disease following Intense Pulsed Light Therapy

niversity of New South Wales0 个研究点目标入组 34 人开始时间: 2022年10月18日最近更新: 2022年10月24日

适应症

试验速览

暂无简介。

•1.Able to read and comprehend English and give informed consent as demonstrated by signing a record of informed consent
•2.Aged 18 years or over
•3.Minimum of 6 months since the onset of self-reported dry eye
•4.Have dry eye symptoms: Ocular Surface Disease Index score (OSDI) of >12 and Contact lens dry eye questionnaire (CLDEQ-8 greater than or equal to 12) (for contact lens users only) and evidence of MG obstruction i.e. meibomian gland secretion score greater Ethan or equal to 12
•5.May or may not use soft contact lenses
•6.All prescription medications have been used consistently for at least 3 months prior to the study, and no planned changes for the duration of the trial
•7.Willing to comply with the study visit schedule and adhere to instructions as directed by the Investigator

•1. Any active anterior segment disease
•2.Any eyelid abnormality including lid lacerations
•3.Patients who are currently using topical ocular medication or have used topical ocular medication within 12 weeks of the first visit
•4.Any systemic disease that may affect ocular health e.g. Graves disease, and auto-immune diseases such as ankylosing spondylitis, multiple sclerosis, and systemic lupus erythematosus;
•5.Gas permeable contact lens wearer (including ortho-k) within 6 months of the first visit
•6.Anyone who has received clinical skin treatments within the prior 2 months, or implants beneath the treatment area including tattoos, semi-permanent makeup, or pigmented lesions
•7.Dark pigmented skin tone according to Fitzpatrick scale V/VI (very dark or black skin), which is prone to skin damage, such as discoloration or scarring after IPL treatment (according to the manufacturer’s guidelines)
•8.Skin cancer, the user of photosensitive drugs /foods
•9.Anyone who has previously received IPL therapy for dry eye treatment
•10.Pregnancy or breastfeeding.

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