Calculation of Platelet-rich Plasma Preparation Yield From Baseline CBC Platelet Count
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- Platelet yield
研究概览
简要总结
This is a study to determine 1) the consistency of platelet-rich plasma produced by several methods, and 2) whether the platelet content of platelet-rich plasma can be accurately estimated from a baseline CBC platelet count.
详细描述
In the first phase of this study a baseline CBC platelet count will be performed on each subject and then platelet-rich plasma (PRP) prepared from the same blood sample by six different methods. The platelet count will be measured in each PRP preparation and compared to the CBC platelet count to determine the platelet yield for each method.
In the second phase of the study a baseline CBC platelet count will be performed on each subject and then platelet-rich plasma (PRP) prepared from the same blood sample by six different methods. The CBC platelet count will be used to calculate the estimated platelet content of each sample/method based on the platelet yields determined in the first phase. The platelet count will be measured in each PRP preparation and compared to the estimated platelet content to determine the predictive accuracy for each method.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 21 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •English speaking
排除标准
- •platelet count < 150,000
- •platelet count > 350,000
- •History of blood disorder
- •History of altered platelet function
- •History of chemotherapy or radiation therapy
结局指标
主要结局
Platelet yield
时间窗: within 8 hours of blood draw
the number of platelets in a PRP sample as a percentage of the number of platelets in the blood from which the PRP was prepared.
Platelet yield estimate accuracy
时间窗: within one month of final data collection
standard deviation of the difference between the estimated platelet yield and the actual platelet yield.
次要结局
未报告次要终点
研究者
Theodore Harrison, MD
Principal Investigator
Harrison, Theodore, M.D.