Impact of Fish Oil Supplementation in 3rd Trimester of Pregnancy on Maternal and Offspring Health
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 533
- 试验地点
- 1
- 主要终点
- Gestation length
研究概览
简要总结
The aim of the trial is to investigate the effect of daily supplementation with 2.7 grams of long chain n-3 fatty acids during the third trimester of pregnancy. In 1990, 533 pregnant women, while they were in gestational week 30, were randomized to fish oil supplements providing the mentioned amount of long chain n-3 fatty acids, olive oil supplements, or no supplements; they were asked to take the supplements until delivery. Health outcomes were assessed during pregnancy and delivery. Further, offspring health and development has been examined during the ensuring two decades by making linkages to the rich Danish health and administrative registries, by asking the offspring to complete web-based questionnaires, and by examining the offspring physically.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 20 Years 至 50 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Healthy pregnant women in gestation week 30
排除标准
- •Bleeding episodes during pregnancy
研究组 & 干预措施
No oil supplement
These women received no capsules with oil
Olive oil
These women received 4 1-g capsules with olive oil per day from gestational week 30 until delivery
干预措施: Olive oil (Dietary Supplement)
Fish oil supplementation
These women received 4 1-g capsules of fish oil per day providing 2,7 grams long chain n-3 fatty acids per day, from gestation week 30 until delivery
干预措施: Fish oil (Dietary Supplement)
结局指标
主要结局
Gestation length
时间窗: 1989-1990 (1 year)
We assesed impact of fish oil supplementation in pregnancy on timing of spontaneous delivery
次要结局
未报告次要终点