Prediction Value of Perfusion and Dual Energy Computer Tomography for Microvascular Invasion in Hepatocellular Carcinoma
试验速览
- 阶段
- 不适用
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- Pefusion parameters
研究概览
简要总结
The aim of this study is to evaluate the hepatic perfusion computer tomography and dual energy computer tomography in the assessment of tumor characterization of Hepatocellular carcinoma in patients with resectable Hepatocellular carcinoma by comparing the quantitative parameters computer tomography obtained with the pathological data of the surgical specimens.
详细描述
Dual-energy computer tomography and perfusion computer tomography (General Electric revolution Hight definition Gemstone™ Spectral Imaging) will be performed in all patients. Iodine concentration and quantitative perfusion parameters of the Hepatocellular carcinoma and surrounding liver parenchyma data will be compared with the pathological results.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •A diagnosis of Hepatocellular carcinoma made according to the guidelines of the American Association for the study of the Liver
- •Affiliation to a national health insurance
- •An indication for hepatic resection during the decision-making stage
- •A request for a pre-operative Computer Tomography in our radiology unit
- •An affiliation to a social security
- •Informed consent given by the patient
排除标准
- •Previous treatments of Hepatocellular carcinoma (medicated or surgical)
- •Patient under tutorship or curatorship
- •Pregnant or lactating woman
研究组 & 干预措施
perfusion computed tomography
Will be realsed before liver surgery
干预措施: perfusion Computed Tomography (Radiation)
结局指标
主要结局
Pefusion parameters
时间窗: 5 minutes
correlation between pre-operative imaging data and histological data of Hepatocellular carcinoma
次要结局
- Pathological examination(1 month)