Comparison of Magnetic Resonance Techniques for the Measurement of Cerebral Blood Perfusion
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- ASL perfusion MRI data
研究概览
简要总结
In this project, we aim at implementing a te-ASL sequence and to compare it to two reference ASL sequences with a fixed PLD on healthy individuals. On the one hand, the te-ASL sequence will be compared against a 3D pCASL with a PLD of 1800 ms, as the current reference according the Consensus of the ISMRM perfusion study group and the European consortium for ASL in dementia. On the other, as the implemented te-ASL sequence will have a 2D readout, it will also be compared to a 2D pCASL ASL sequence with the same PLD, in order to be able to disentangle differences due to the dynamic PLD scheme from those arising from the different read-out schemes.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •To sign the study informed consent form approved by the corresponding authorities.
- •Healthy men and women (older than 18 years old).
排除标准
- •Inability or unwillingness to give written informed consent or communicate with the study staff or illiteracy.
- •Any contraindication to perform brain MRI procedure (e.g. pacemaker, MRI-incompatible aneurysm clips).
结局指标
主要结局
ASL perfusion MRI data
时间窗: Through study completion, an average of 1 year
Quantification of cerebral blood flow
次要结局
未报告次要终点