Comparison Between Erythropoietin-enhanced Albumin Platelet-rich Fibrin and Albumin Platelet-rich Fibrin in Transcrestal Sinus Lifting With Simultaneous Implant Placement
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- Change in pain scores
研究概览
简要总结
Background: Dental implant therapy in the posterior maxilla may be difficult owing to limited bone height after dental extraction with sinus pneumatization. Several approaches for sinus floor elevation have been documented, and hence trans crestal sinus lifting with albumin platelet rich plasma.
Aim of the study: To compare between erythropoietin and albumin platelet rich fibrin transcrestal sinus lifting versus albumin platelet rich fibrin transcrestal sinus lifting using piezoelectric device in patients with atrophic maxilla.
Methods: This study will be carried out as a randomized
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 20 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Residual bone height not less than 5 mm measured from crestal bone to sinus floor.
- •Both genders.
- •Good oral hygiene
- •No previous surgery or radiation treatment on the maxillary sinus
排除标准
- •Recent radiation therapy in maxilla.
- •Uncontrolled systemic diseases such as diabetes mellitus.
- •Heavy smoker (those who smoke ≥ 25 cigarettes a day).
- •Alcohol abuse.
- •Patient on anticoagulant drug
- •Severe allergic rhinitis.
- •Tumor or large cyst in the maxillary sinus.
- •Oroantral fistula.
- •Presence of acute or chronic sinus pathoses or sinus membrane perforation.(
结局指标
主要结局
Change in pain scores
时间窗: up to 14 days
pain will be assessed through a 10 point visual analogue scale (VAS). (0-1=none, 2-4=mild, 5-7=moderate, 8-10=severe).
Change in edema
时间窗: up to 14 days
Edema will be assessed as follows: 1. None (no swelling) 2. Mild (intraoral swelling confined to the surgical field) 3. Moderate (extra oral swelling in the surgical zone) 4. Severe (extraoral swelling spreading beyond the surgical zone)
Change in implant stability
时间窗: immediate and 4 months
implant stability will be assessed using ostell device
次要结局
- Change in bone gain(baseline and 4 months)
- Change in bone density(baseline and 4 months)