NCT05952050招募中不适用
Effect of Different Administration Routes of Dexmedetomidine on Postoperative Delirium in Elderly Patients Undergoing General Anesthesia
Boston Intelligent Medical Research Center, Shenzhen United Scheme Technology Co., Ltd.1 个研究点 分布在 1 个国家目标入组 120 人开始时间: 2023年8月1日最近更新:
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 120
- 试验地点
- 1
- 主要终点
- The frequency of delirium during the first 3 postoperative days
研究概览
简要总结
Intravenous dexmedetomidine has been reported to decrease the occurrence of postoperative delirium (POD) in elderly patients. Nevertheless, some previous studies have indicated that intratracheal dexmedetomidine and intranasal dexmedetomidine are also effective and convenient. The current study aimed to compare the effect of different administration routes of dexmedetomidine on POD in elderly patients.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 65 Years 至 99 Years（Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Older than 65 years; General anesthesia for more than two hours;
排除标准
- 未提供
研究组 & 干预措施
Intranasal dexmedetomidine
Experimental
干预措施: Dexmedetomidine (Drug)
Intravenous dexmedetomidine
Active Comparator
干预措施: Dexmedetomidine (Drug)
结局指标
主要结局
The frequency of delirium during the first 3 postoperative days
时间窗: 3 days
次要结局
- The incidence of sleep quality(3 days)
- The incidence of postoperative sore throat(3 days)
研究者
研究点 (1)
Loading locations...
相似试验
已完成
4 期
Efficacy of Low-dose Dexmedetomidine to Prevent Delirium in Liver Transplant PatientsLiver TransplantationNCT02245256Seoul National University Hospital217
Unknown
不适用
Effect of Intraoperative Dexmedetomidine on Postoperative Delirium in Elderly Patients Undergoing Robot-assisted Pancreaticoduodenectomy: a Randomized Controlled StudyDelirium in Old AgeNCT05274789Chinese PLA General Hospital300
已完成
不适用
Effect of Intraoperative Dexmedetomidine on Postoperative Delirium in Elderly Patients Undergoing Major Abdominal SurgeryDelirium in Old AgeNCT05436964Chinese PLA General Hospital268
Unknown
4 期
How Different Sedatives Affect Hip Fracture Patient's Postoperative DeliriumDelirium in Old AgeNCT03346226Shanghai Zhongshan Hospital1,000
Unknown
不适用
Dexmedetomidine and Delirium in Elderly PatientsDelirium, Dexmedetomidine, Postoperative PCANCT03938831Korea University Guro Hospital60