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临床试验/NCT03304197
NCT03304197已完成不适用

How Does Altering the Composition of Ingested Fluids Affect Hydration Status Whilst Cycling?

University of Exeter1 个研究点 分布在 1 个国家目标入组 15 人开始时间: 2017年9月11日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
15
试验地点
1
主要终点
Absorption of fluid through the gut

研究概览

简要总结

This study will evaluate the effects manipulating ingested fluids can have on hydration status and cycling performance. There will be 4 different conditions.

详细描述

Being dehydrated can decrease endurance exercise performance. The investigators wish to test which of three drinks is most effective at re-hydrating cyclists and if this affects performance. Subjects will undertake 4 tests: once dehydrated, once hydrated with water, once hydrated with a sports-specific drink, and once with an altered sports drink. Blood samples will be taken and expired gasses will be sampled at various time points throughout the tests for later analysis. A small amount of labelled water will be consumed with each drink, a technique which will allow us to quantify the absorption of each of the drinks.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
主要目的
Treatment
盲法
Double (Participant, Investigator)

盲法说明

Doubly-blinded & randomised using an online randomisation website.

入排标准

年龄范围
18 Years 至 50 Years(Adult)
性别
All
接受健康志愿者
是

入选标准

  • •Highly trained cyclists (vo2max >55 ml/kg/min, PPO (peak power output) > 4 w/kg)
  • •Training at least 4 times a week
  • •Females must be taking an oral contraceptive, or using the contraceptive implant

排除标准

  • •Recent history of musculoskeletal injury
  • •Diagnosed cardiovascular disease
  • •Regular use of nutritional supplements that may interfere with the protocol

研究组 & 干预措施

Dehydrated

Experimental

90 minutes cycling, without the ingestion of any fluids, followed by a 15 minute cycling time trial test

干预措施: Dehydrated (Other)

Hypotonic

Experimental

90 minutes cycling, with the ingestion of six 250 ml carbohydrate (6g sucrose, 3g glucose) drinks, followed by a 15 minute cycling time trial test

干预措施: Hypotonic (Dietary Supplement)

Isotonic

Experimental

90 minutes cycling, with the ingestion of six 250 ml carbohydrate (6g glucose, 3g fructose) drinks, followed by a 15 minute cycling time trial test

干预措施: Isotonic (Dietary Supplement)

Placebo

Experimental

90 minutes cycling, with the ingestion of six 250 ml taste-matched water drinks, followed by a 15 minute cycling time trial test

干预措施: Placebo (Dietary Supplement)

结局指标

主要结局

Absorption of fluid through the gut

时间窗: To begin 10 minutes after the completion of the 90 minute steady-state cycle

Absorption of drinks through the gut will be measured using 2 boluses of deuterated water. This will be consumed alongside 2 of the drinks, and blood samples will be used to quantify enrichment. Total body water calculations are required to provide corrections in equations related to D2O. H218O will be consumed in order to quantify total body water: this will be provided in a single bolus before each trial.

次要结局

  • Work done (kJ) during 15 minute cycling time-trial(Throughout the 90 minute steady-state cycle & the 15 minute time trial.)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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