Assessment of swallowing, nutritional status, and markers of inflammation and oxidative stress in children and adolescents with cystic fibrosis.

Emilia Addison Machado Moreira0 个研究点目标入组 86 人开始时间: 2011年11月25日最近更新: 2020年1月13日

适应症

试验速览

暂无简介。

•Experimental group: children and adolescents diagnosed with cystic fibrosis with impairment classified as moderate score of Schwachman-Kulczicki. Clinically stable for at least thirty days prior to data collection.
•Control group: children and adolescents without cystic fibrosis and without inflammatory symptoms, normal for weight, and paired in age and sex with the cystic fibrosis group.

•Experimental group: patients on antibiotics during or even a month before the day of collection and those in period of pulmonary exacerbation. Individuals undergoing mechanical ventilation, intubated-tracheotomised (up to 3 months before or at the time of assessment), undergoing nutritional-enteral therapy, or suffering from cerebral palsy, autism, encephalopathy, Down’s syndrome and other conditions that would compromise swallowing, in a terminal stage. Individual suffering from inflammatory (asthma, intestinal inflammatory illness, rheumatic illness), neurological or degenerative illnesses, renal insufficiency and/or diabetes mellitus, or using antibiotics and/or hormones or non-hormonal anti-inflammatory drugs, up to 6 months before the study.
•Control group: Individuals suffering from inflammatory (asthma, intestinal inflammatory illness, rheumatic illness), neurological or degenerative illnesses, renal insufficiency and/or diabetes mellitus, or using antibiotics and/or hormones or non-hormonal anti-inflammatory drugs, up to 6 months before the study. Individuals with symptoms of gastroesophageal reflux (heartburn, regurgitation of food, frequent cough).

发起方

Emilia Addison Machado Moreira