Effect of Milk and Cheese on Fecal Fat Excretion and Blood Lipid
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 15
- 试验地点
- 1
- 主要终点
- Fecal fat excretion
研究概览
简要总结
The aim is to study the effect of milk versus cheese on fecal fat excretion and blood lipids. To do this, a randomized crossover intervention study with 3 14-day periods (control diet, milk diet, cheese diet) will be conducted in 16 young males. Fasting blood samples will be collected before and after each period, and fecal samples will be collected for the last 5 days in each period.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Prevention
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 50 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •Healthy males
- •BMI 20-28 mg/m2
排除标准
- •Medicine use
- •Dietary supplements
- •Lactose intolerance, milk allergy
- •Dislike of dairy products
- •Excessive physical activity (> 10h/wk)
- •Known chronic illnesses
研究组 & 干预措施
Milk diet
Diet with a high content of milk
干预措施: Dietary intervention (high milk content) (Other)
Control diet
Diet without dairy products
干预措施: Dietary intervention (without dairy products) (Other)
Cheese diet
Diet with a high content of cheese
干预措施: Dietary intervention (high cheese content) (Other)
结局指标
主要结局
Fecal fat excretion
时间窗: During day 10-14 in each period
Total excretion of fecal fat (grams/day)avaraged over five days
次要结局
- Total, HDL and LDL cholesterol(Day 1 and 14 in each period)
- Triglycerides(Day 1 and 14 in each period)
- Appetite sensation(Assessed on day 1, 8 and 14 in each period)