NCT01296269Unknown不适用
Effects of Intranasal Oxytocin and Vasopressin on Social Behavior in Healthy Controls
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 入组人数
- 150
- 试验地点
- 1
- 主要终点
- allocations of monetary units
研究概览
简要总结
The purpose of this study is to investigate the role of a one-time intranasal administration of the oxytocin, vasopressin, or placebo on prosocial decision making such as cooperation and altruism in a healthy population of student controls.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- Double (Participant, Care Provider)
入排标准
- 年龄范围
- 18 Years 至 35 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •healthy controls
排除标准
- •Past or present psychiatric, neurological, endocrinological or severe chronic medical illness.
- •Use of medications or drugs that would interfere with study results. This includes steroids, medications for psychiatric symptoms like anxiety or depression, stimulants, and medications for high blood pressure. Participants will be asked to tell the investigators of any medications or drugs that they are taking. The investigators will consider the drug interactions with oxytocin and vasopressin prior to study, and participants will not be able to participate in the study if the drug interactions could be dangerous.
- •history of drug or alcohol addiction
- •Pregnancy or Nursing Status: Because of the risk to an unborn fetus or infant, women who are pregnant or nursing are excluded from this protocol. All females will have a pregnancy test performed no more than 24 hours before each drug administration and will not be able to participate if the pregnancy test is positive.
研究组 & 干预措施
Vasopressin
Experimental
vasopressin condition
干预措施: Arginine Vasopressin (Drug)
oxytocin
Experimental
oxytocin condition (syntocinon)
干预措施: Oxytocin (Drug)
placebo
Placebo Comparator
干预措施: placebo (Drug)
结局指标
主要结局
allocations of monetary units
时间窗: approximately 45 minutes after intranasal administration of vasopressin, oxytocin, or placebo
Participants will make decisions regarding the allocation of monetary units between themselves and other participants. We will measure the quantity of monetary units kept for themselves vs. given to other participants
次要结局
- mood as measured via the visual analog scale(approximately one hour and fifteen minutes after administration of oxytocin, vasopressin or placebo)
研究者
研究点 (1)
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