Procalcitonin Has a Role to Play in Prediction of Intra-amniotic Subclinical Infection.
试验速览
- 阶段
- 不适用
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- The correlation between procalcitonin level in PPROM and C-reactive protein level in neonates.
研究概览
简要总结
It is hypothesized that the procalcitonin has a role to play in prediction of intra-amniotic subclinical infection.
详细描述
Study population
- This study will be conducted at the department of Obstetrics and Gynecology recruiting pregnant women selected from the attendees of antenatal clinic, emergency department and from inpatient wards of Ain Shams University Maternity Hospital from Mars2014.
- This study will include 100 pregnant women these cases will be divided into 2 groups:
- Group 1: Healthy preterm Group: will include 50 pregnant females all at 24-34 weeks of gestational age .
- Group 2: Preterm premature rupture of membrane Group: will include 50 pregnant females all at 24-34 weeks of gestational age
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 20 Years 至 40 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- 未提供
排除标准
- 未提供
研究组 & 干预措施
procalcitonin in blood
-Group 1: Healthy preterm Group: will include 50 pregnant females all at 24-34 weeks of gestational age .
干预措施: procalcitonin (Drug)
plasma of blood
-Group 2: Preterm premature rupture of membrane Group include 50 pregnant women
干预措施: procalcitonin (Drug)
procalcitonin,prematureruptureofmembrane in blood
Complete history including (special habits like smoking and alcohol taking, menstrual history especially LMP, medical diseases, past obstetric history including duration, mode of delivery for each pregnancy, and if there were fetal or maternal complications).
Physical examination including (general condition, height, weight, vital signs).-Ultrasound to execlude multiple pregnancies, IUFD and to confirm oligohydraminos in group2.
The venous blood samples will be taken for measuring of -Procalcitonin in mothors -CRP and WBCs in mothers to detect infection -CRP in neonates of mothers of group 2.
They will be asked for their permission and consent.
干预措施: procalcitonin (Drug)
结局指标
主要结局
The correlation between procalcitonin level in PPROM and C-reactive protein level in neonates.
时间窗: one year
The correlation between procalcitonin level in PPROM and C-reactive protein level in neonates
次要结局
- Procalcitonin. - C-reactive protein. - White blood cells count (total and diffrantiated). -C-reactive protein in neonates of groub 2.(one year)
研究者
Alaa Sayed Hassanin
Lecturer
Ain Shams Maternity Hospital