Clinical Significance of Peri-appendiceal Abscess and Phlegmon in Acute Complicated Appendicitis Patients Undergoing Emergency Appendectomy: A Single-center Retrospective Study
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 150
- 主要终点
- The post-operative length of hospital stay (LOS)
研究概览
简要总结
This study aim to analyze the clinical data of patients who underwent emergency appendectomy for acute complicated appendicitis with peri-appendiceal abscess or phlegmon, identify factors influencing the post-operative length of hospital stay (LOS), and improve treatment strategies.
详细描述
Appendicitis is defined as inflammation of the vermiform appendix and worldwide is the most common reason for emergency abdominal surgery. Globally, the annual incidence is 96.5 to 100 cases per 100 000 adult population. For acute uncomplicated appendicitis, antibiotic therapy has emerged as the primary treatment, often allowing patients to avoid surgery. However, the management of acute complicated appendicitis requires careful consideration of various treatment options.
Complicated appendicitis, characterized by peri-appendiceal phlegmon or abscess formation, presents additional challenges and often requires a more comprehensive treatment approach. Management strategies have evolved to incorporate both conservative and surgical treatments, tailored to the patient's condition. Typically, for early-stage appendicitis (duration of symptoms ≤72 hours) with peri-appendiceal phlegmon, surgical treatment is recommended, while late-stage appendicitis (duration of symptoms >72 hours) or cases with peri-appendiceal abscess formation are initially managed conservatively with percutaneous drainage and antibiotics. Despite this, some patients still prefer surgical intervention for various reasons. Currently, there is a lack of studies on the outcomes of patients with acute complicated appendicitis who opt for surgery over conservative treatment, highlighting the need for further research.
In practical terms, the benefits and risks of all treatment options should be thoroughly presented and discussed. Recommendations for surgery versus a conservative treatment-first approach should be based on individual clinical and radiographic findings, as well as patient treatment expectations and preferences. This study aim to investigate the clinical significance of peri-appendiceal abscess or phlegmon in the surgical management of acute complicated appendicitis.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 100 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients who were aged ≥18 years, Patients who were clinically diagnosed with acute appendicitis, Patients who had a peri-appendiceal abscess or phlegmon on CT scan, Patients who opted to undergo immediate emergency surgery as their primary choice, Patients who refused conservative treatment first (antibiotic therapy and ultrasound/CT-guided drainage).
排除标准
- •Patients younger than 18 years, Patients have a history of prior malignancies, Patients with diffuse peritonitis, Patients with incomplete clinical or pathological records.
结局指标
主要结局
The post-operative length of hospital stay (LOS)
时间窗: January 01, 2025 to December 31, 2025.
次要结局
未报告次要终点