Efficacy Of Ultrasound Guided External Oblique Intercostal Plane Block for Postoperative Analgesia in Patients Undergoing Subcostal Nephrectomy: A Randomised Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 25
- 试验地点
- 1
- 主要终点
- Time for first rescue analgesia
研究概览
简要总结
The patients will be randomly allocated into two equal groups using a computer program.
Group A: will receive external oblique intercostal block after induction. Group B: will receive postoperative morphine per patient request.
详细描述
General anaesthesia induction will be achieved using fentanyl 1µg/kg (IV), propofol 2mg/kg (IV), and0.5mg/kg of IV Atracurium. General anaesthesia will be maintained with mechanical ventilation with isoflurane with O2 \ Air mixture.
During anaesthesia maintenance Intraoperatively, if BP or heart rate (HR) increase more than 20% from baseline, intravenous morphine will be given to stabilize the patients' haemodynamics.
All patients will receive 1g intravenous paracetamol and 4mg ondansetron 8mg dexamethasone.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •- Eligible patients will be older than 18 years old with American society of anestheologist ASA physical status I, II and III scheduled for Trans-Abdominal ( Anterior Subcostal) Nephrectomy
排除标准
- •Patients who are:
- •Unable to cooperate.
- •Patients who have allergy to any of the study drugs.
- •Patients who are on opioids.
- •Known abuse of alcohol or medication.
- •Local infection at the site of injection or systemic infection.
- •Pregnancy
- •Patients with coagulation disorders or on anticoagulation therapy
结局指标
主要结局
Time for first rescue analgesia
时间窗: day 0
hours
次要结局
- VAS score(24 hours)
- rescue analgesics(24hous)
研究者
Amal Gouda Elsayed Safan
lecturer of anaethesia
Menoufia University