Efficacy Of Ultrasound Guided External Oblique Intercostal Plane Block for Postoperative Analgesia in Patients Undergoing Subcostal Nephrectomy: A Randomised Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 25
- 试验地点
- 1
- 主要终点
- Time for first rescue analgesia
研究概览
简要总结
The patients will be randomly allocated into two equal groups using a computer program.
Group A: will receive external oblique intercostal block after induction. Group B: will receive postoperative morphine per patient request.
详细描述
General anaesthesia induction will be achieved using fentanyl 1µg/kg (IV), propofol 2mg/kg (IV), and0.5mg/kg of IV Atracurium. General anaesthesia will be maintained with mechanical ventilation with isoflurane with O2 \ Air mixture.
During anaesthesia maintenance Intraoperatively, if BP or heart rate (HR) increase more than 20% from baseline, intravenous morphine will be given to stabilize the patients' haemodynamics.
All patients will receive 1g intravenous paracetamol and 4mg ondansetron 8mg dexamethasone.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •- Eligible patients will be older than 18 years old with American society of anestheologist ASA physical status I, II and III scheduled for Trans-Abdominal ( Anterior Subcostal) Nephrectomy
排除标准
- •Patients who are:
- •Unable to cooperate.
- •Patients who have allergy to any of the study drugs.
- •Patients who are on opioids.
- •Known abuse of alcohol or medication.
- •Local infection at the site of injection or systemic infection.
- •Pregnancy
- •Patients with coagulation disorders or on anticoagulation therapy
研究组 & 干预措施
external oblique intercostal block after induction
After induction of general anesthesia, external oblique intercostal blocks will be performed with patients positioned in the supine position with their ipsilateral arm abducted.
Initially the probe is placed in a cephalad to caudad paramedian direction at the anterior axillary line, and the external oblique muscle identified at the level ribs 6 and 7 in line with the xiphoid process. To confirm correct identification of the external oblique muscle, With 17gauge echogenic ultrasound needle will be advanced in plane from a superomedial-to-inferolateral direction, through the external oblique muscle.30 ml of bupivacaine 0.25% will be administered incrementally.
干预措施: external oblique intercostal block (Procedure)
postoperative morphine per patient request
In this group no block will be done only morphine will be given intraoperatively- according to hemodynamic change and postoperative by morphine per patient request
结局指标
主要结局
Time for first rescue analgesia
时间窗: day 0
hours
次要结局
- VAS score(24 hours)
- rescue analgesics(24hous)
研究者
Amal Gouda Elsayed Safan
lecturer of anaethesia
Menoufia University