Evaluation of Acetabular Perfusion After Ganz Osteotomy by Positron Emission Tomography
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 12
- 试验地点
- 2
- 主要终点
- changes in blood flow
研究概览
简要总结
The purpose of this study is to examine the blood flow in acetabulum after periacetabular osteotomy by Positron Emission Tomography (PET).
详细描述
As a consequence of periacetabular osteotomy the blood flow in acetabulum is decreased. After periacetabular osteotomy has been performed there is fine contact between the osteotomised acetabulum and the rest of the pelvis and the potential for healing is good. However, it has not been investigated how much the blood flow in acetabulum is changed after surgery. The blood flow is considered to be vital for how the pelvis heals after surgery. Most likely, the blood flow is important in relation to which degree osteoarthritis can be prevented after periacetabular osteotomy.
It is possible to estimate the blood flow by Positron Emission Tomography of the dysplastic hip joint pre- and postoperatively. In this study the blood flow and fluoride uptake is quantified by Positron emission tomography based on measurements of O-15 water and F-18 fluoride.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with radiologically diagnosed hip dysplasia (CE-angle < 25°).
- •Patients with osteoarthritis graded 0, 1 or 2 defined according to Tönnis' classification. Patients with pain from hip
- •Age > 18 years.
- •Minimum 110° flexion in hip joint and closed growth zones in the pelvic.
- •Informed consent.
排除标准
- •Patients with neurological diseases
- •Patients with calvé-Legg-Perthes syndrome.
- •Patients where an femoral intertrochanteric osteotomy is necessary.
- •Patients with medical sequelae after earlier hip surgery.
- •Females who are pregnant.
- •Patients with metal implants.
结局指标
主要结局
changes in blood flow
时间窗: within the first three weeks after operation
次要结局
- fluoride uptake(within the first three weeks after operation)