Acute Hemodynamic Changes During Paracentesis

Completed

• Conditions: Liver Cirrhosis; Tense Ascites
• Interventions: Procedure: routine therapeutic paracentesis

• Registration Number: NCT02996188
• Lead Sponsor: Universitätsmedizin Mannheim

Brief Summary

The aim of our study was to evaluate hemodynamic changes during routine paracentesis in tense ascites using non-invasive inert gas rebreathing.

Detailed Description

Not available

Study Timeline

• Study Start: 2012-06
• Primary Completion: 2013-11
• Study Completion: 2013-11
• Status Verified: 2016-12
• Study First Submitted: 2016-12-14
• Study First Submitted QC: 2016-12-14
• Last Update Submitted: 2016-12-14
• Study First Posted: 2016-12-19
• Last Update Posted: 2016-12-19

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 36

Inclusion Criteria

• refractory tense ascites with indication for therapeutic paracentesis

Exclusion Criteria

• pregnancy
• inability to give inform consent
• inability to perform rebreathing maneuver

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Patients with refractory tense ascites	routine therapeutic paracentesis	-

Primary Outcome Measures

Name	Time	Method
change in cardiac output	30 minutes	prior to and after paracentesis
change in systemic vascular resistance	30 minutes	prior to and after paracentesis