The Impact of 4% Sodium Bicarbonate Additive During Potassium Chloride Replacement on Pain and Incidence of Phlebitis for Adult Patients in a Medical Surgical Unit: A Randomized Double Blinded Controlled Study
试验速览
- 阶段
- 4 期
- 状态
- 终止
- 发起方
- 入组人数
- 17
- 试验地点
- 1
- 主要终点
- Number of Participants With Indicated Findings
研究概览
简要总结
The purpose of this study is to examine the impact of 4% sodium bicarbonate additive during peripheral intravenous potassium chloride replacement therapy for adult patients in a Medical/Surgical unit. Using a randomized controlled double blinded experimental study design, patients who are 21 years or older are alert, awake, and oriented at the time of enrollment and have been ordered peripheral intravenous potassium chloride replacement will be recruited from one Medical/Surgical during the first 24-48 hours of their admission.
详细描述
The specific aim of the study is:
Aim 1: To compare patient outcomes (phlebitis, pain at peripheral IV insertion site, frequency of changing IV access, and time for administration) between the experimental (4% sodium bicarbonate additive during peripheral intravenous potassium chloride replacement therapy) and control (standard of practice of no 4% sodium bicarbonate additive during peripheral intravenous potassium chloride replacement therapy) groups.
Aim 2: To compare number and type of nursing interventions done during peripheral intravenous potassium chloride replacement therapy between the experimental (4% sodium bicarbonate additive during peripheral intravenous potassium chloride replacement therapy) and control (standard of practice of no 4% sodium bicarbonate additive during peripheral intravenous potassium chloride replacement therapy) groups.
Aim 3: To compare attrition rates and reasons between the experimental (4% sodium bicarbonate additive during peripheral intravenous potassium chloride replacement therapy) and control (standard of practice of no 4% sodium bicarbonate additive during peripheral intravenous potassium chloride replacement therapy) groups.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- Double (Participant, Care Provider)
入排标准
- 年龄范围
- 21 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •admitted to the medical/surgical unit within the last 24 to 48 hours
- •awake, alert, and oriented times three
- •21 years old and greater
- •receiving first peripheral intravenous potassium chloride replacement therapy as ordered by physician or ARNP as part of care and regardless of research
- •potassium level of 3.5 mmol/L or less.
排除标准
- •patients who have been in the medical/surgical unit more than 48 hours.
- •altered mental status defined as not being awake, alert, and oriented times three
- •patients who already received intravenous potassium chloride replacement during the current admission and with the current IV access
- •patients receiving intravenous potassium replacement therapy through a central line
- •patients that are not ordered potassium replacement by physician or ARNP as part of their care while hospitalized.
研究组 & 干预措施
Neut (4%sodium bicarbonate additive)
4% sodium bicarbonate additive during intravenous potassium chloride replacement.
干预措施: potassium chloride replacement (Drug)
Neut (4%sodium bicarbonate additive)
4% sodium bicarbonate additive during intravenous potassium chloride replacement.
干预措施: Experimental - 4% Sodium Bicarbonate (Drug)
Control
standard of practice potassium chloride replacement (with no additive)
干预措施: potassium chloride replacement (Drug)
结局指标
主要结局
Number of Participants With Indicated Findings
时间窗: Up to 4 hours
outcomes - phlebitis, pain at peripheral intravenous insertion site, frequency of changing IV access, and time for administration. experimental - 4% sodium bicarbonate additive during peripheral intravenous potassium chloride replacement therapy. control - standard of practice of no 4% sodium bicarbonate additive during peripheral intravenous potassium chloride replacement therapy.
次要结局
- Number of Participants Nursing Interventions(Up to 4 hours)
- Attrition Rates(Up to 4 hours)