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临床试验/PACTR202002644579177
PACTR202002644579177Other未知

Superiority Trial of Intermittent Treatment with Dihydroartemisinin–Piperaquine versus Sulfadoxine–Pyrimethamine for the Prevention of Malaria during Pregnancy

Royal Society of Tropical Medicine and Hygiene0 个研究点目标入组 250 人开始时间: 2020年2月13日最近更新:
适应症

试验速览

阶段
未知
状态
Other
发起方
入组人数
250

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional

入排标准

年龄范围
13 Year(s) 至 18 Year(s)(—)
性别
Female

入选标准

  • Pregnant women aged 15-49 years
  • Attending antenatal clinic (ANC) for the first time in this current pregnancy
  • Gestation of 16-20 weeks (as assessed by LMP and/or ultra-scan)
  • HIV-negative pregnant women
  • No current history of receiving IPTp-SP
  • Willing to provide informed written consent
  • Planning to stay in Maiduguri and attending ANC and have child delivery at University of Maiduguri Teaching Hospital, Maiduguri

排除标准

  • A history of allergic reaction to sulfa drugs (SP or cotrimoxazole) or DP
  • Having haemoglobin level < 7 g/dl
  • Positive test for falciparum malaria
  • History of receipt of antimalarials or antibiotics with antimalarial activity (cotrimoxazole, rifampin, doxycycline, clindamycin, tetracycline, erythromycin, azithromycin, chloramphenicol) in the past month
  • Women with sickle cell disease
  • Women with high-risk pregnancies (presence of high blood pressure and diabetes)
  • HIV- Positive women

研究者

发起方
Royal Society of Tropical Medicine and Hygiene

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