Effects of Smoking Environment on Craving and Smoking: A Pilot Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 41
- 试验地点
- 2
- 主要终点
- Change in self-report craving measured by the cue-exposure rating scale
研究概览
简要总结
The goal of this study is to evaluate the effects of exposure to standard smoking environments on ability to resist smoking as measured with a Delay to Smoking Task. The results of this study will inform whether the Delay to Smoking Task is a sensitive measure for evaluating environment-provoked craving and smoking behavior.
详细描述
Adult smokers (n=25) will complete 4 visits and a 6 month follow-up phone call. Participants will complete a Delay to Smoking Task following 6 hours smoking abstinence. The task involves viewing pictures of smoking and non-smoking locations and participants will have the choice to smoke a cigarette at any time during the session. A monetary reinforcer will be provided for each 6-minute period that a participant resists smoking. Once participants stop the task they can choose to smoke as much or a little as they want for the next 30 minutes. Participants will be provided with a smoking tab. Each cigarette they light will cost them from their tab. Measurements of tobacco craving, emotion ratings, and nicotine withdrawal will be assessed.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 55 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •generally healthy
- •between the ages of 18 and 55
- •smoking an average of 5 cigarettes per day for at least one year
- •breath CO level > 8 ppm (if ≤ 8 ppm, then NicAlert Strip = 6)
- •no interest in quitting smoking for the duration of time required for the experiment
排除标准
- •inability to attend all required experimental sessions
- •use of psychoactive medications
- •use of smokeless tobacco
- •current alcohol or drug abuse
- •use of illegal drugs as measured by urine drug screen (excluding marijuana)
- •current use of nicotine replacement therapy or other smoking cessation treatment
- •Blood Alcohol Level (BAL) > 0.00
- •use of other tobacco products or e-cigarettes more than 9 days in the past 30 days
结局指标
主要结局
Change in self-report craving measured by the cue-exposure rating scale
时间窗: at 0 minutes, +30 minutes, +60 minutes and following first cigarette
Difference in number of subjects who initiate smoking during the smoking cue Delay to Smoking Task compared to the nonsmoking cue Delay to Smoking Task
时间窗: following start of Delay to Smoking Task, up to 60 minutes
If participant initiates smoking a cigarette during the Delay to Smoking Task
Number of minutes to first puff
时间窗: following start of Delay to Smoking Task, up to +60 minutes
Number of minutes to first puff of cigarette will be recorded for participants that initiate smoking
次要结局
未报告次要终点