Study on Cardiovascular Health, Nutrition and Physical Functioning in Older Adults in Spain (Seniors-ENRICA II)
试验速览
- 阶段
- 不适用
- 状态
- Enrolling By Invitation
- 入组人数
- 4,000
- 试验地点
- 1
- 主要终点
- Executive function limitations on motor response control
研究概览
简要总结
Population aging makes it necessary to identify factors related to unhealthy aging. The purpose of this study is to examine the association between ideal cardiovascular health, diet and other lifestyles and biological risk factors (either clasical or emergent) and the risk of physical and cognitive function impairment and mortality in a cohort of community-living individuals aged 65 years and over.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 65 Years 至 95 Years（Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Non-institutionalized residents in the region of Madrid, Spain.
- •65 years and over
排除标准
- 未提供
结局指标
主要结局
Executive function limitations on motor response control
时间窗: 3 years
GO-NO-GO test.
Functional limitations on balance
时间窗: 3 years
Short Physical Performance Battery (SPPB): Balance test
Functional limitations on strength of legs
时间窗: 3 years
Short Physical Performance Battery (SPPB): Chair Stand test
Functional limitations on activities of daily living
时间窗: 3 years
Activities of Daily Living (ADLs) test
Functional limitations on instrumental activities of daily living
时间窗: 3 years
Instrumental Activities of Daily Living (IADLs) test
Functional limitations on olfactory function
时间窗: 3 years
Pocket Smell test
Cognitive impairment
时间窗: 3 years
Mini-Mental State Examination (MMSE)
Frailty
时间窗: 3 years
Fried criteria
Arterial stiffness estimated by central sistolic blood pressure (CSBP)
时间窗: 3 years
Ambulatory Blood Pressure Monitor using the oscillometric method (Mobil-O-Graph PWA) to estimate CSBP (mmHg) over a 24 hours period
Mortality
时间窗: 3 years
From the National Institute of Statistics of Spain
Functional limitations on strength of hands
时间窗: 3 years
Hydraulic hand dynamometer (Jamar Plus +)
Falls
时间窗: 3 years
From the question: "How many times have you fallen down since the last interview? a) Number of falls; b) Number of injurious falls; c) Number of falls with fracture
Functional limitations on shoulder flexibility
时间窗: 3 years
Back Scratch test
Functional limitations on gait speed
时间窗: 3 years
Short Physical Performance Battery (SPPB): Gait Speed test
Memory function limitations
时间窗: 3 years
Seven Minute Screen (orientation, memory, clock drawing, verbal fluency)
Functional limitations on bicep-femoral flexibility
时间窗: 3 years
Chair Sit and Reach test
Functional limitations on taste function
时间窗: 3 years
NIH Tool Box Taste test
Functional limitations on auditory function
时间窗: 3 years
Audiometry
Executive function limitations on working memory
时间窗: 3 years
Digits Forward test (WAIS-III),
Executive function limitations on programmed motor tasks
时间窗: 3 years
Three Hand Position test of Luria
Arterial stiffness estimated by augmentation index (AI)
时间窗: 3 years
Ambulatory Blood Pressure Monitor using the oscillometric method (Mobil-O-Graph PWA) to estimate AI (%) over a 24 hours period
Arterial stiffness estimated by pulse wave velocity (PWV)
时间窗: 3 years
Ambulatory Blood Pressure Monitor using the oscillometric method (Mobil-O-Graph PWA) to estimate PWV (m/s) over a 24 hours period
24-h systolic and diastolic blood pressure
时间窗: 3 years
Ambulatory Blood Pressure Monitor using the oscillometric method (Mobil-O-Graph PWA) to estimate brachial blood pressure (systolic and diastolic) (mmHg) over a 24 hours period
次要结局
未报告次要终点
研究者
Fernando Rodríguez-Artalejo
Professor of Preventive Medicine and Public Health
Universidad Autonoma de Madrid