EUCTR2017-004153-17-DK进行中（未招募）1 期
Evaluation of the effect of Triheptanoin on fatty acid oxidation and exercise tolerance in patients with debrancher deficiency, glycogenin-1 deficiency and phosphofructokinase deficiency at rest and during exercise. A randomized, double-blind, placebo-controlled, cross-over study. - Triheptanoin in Glycogenoses
Copenhagen Neuromuscular Center0 个研究点目标入组 20 人开始时间: 2018年3月26日最近更新:
适应症
试验速览
- 阶段
- 1 期
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 20
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •- Male/Female Age > 15 years
- •- Genetically and/or biochemically verified diagnosis of GSD III, GSD VII or GSD XV
- •- Capacity to consent
- •- For women in fertile age on contraceptive treatment with: Birth control
- •pills, coil, ring, transdermal hormone patch injection of gestagen or
- •subdermal implant.
- •Are the trial subjects under 18? yes
- •Number of subjects for this age range: 4
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range 14
- •F.1.3 Elderly (>=65 years) yes
- •F.1.3.1 Number of subjects for this age range 2
排除标准
- •- Significant cardiac or pulmonary disease
- •- Pregnancy (confirmed by urine stix or plasma-HCG) or breastfeeding.
- •- Inability to perform cycling exercise
- •- Any other significant disorder that may confound the interpretation of
- •the findings
研究者
相似试验
已完成
2 期
The Effect of Triheptanoin on Fatty Acid Oxidation and Exercise Tolerance in Patients With GlycogenosesTarui DiseaseDebrancher DeficiencyGYG1 DEFICIENCYNCT03642860Rigshospitalet, Denmark3
进行中（未招募）
1 期
The effect of Triheptanoin in adults with McArdle Disease (Glycogen Storage Disease Type V)McArdle Disease Also called: Glycogen Storage Disease Type V or Myophosphorylase DeficiencyMedDRA version: 19.0Level: LLTClassification code 10026970Term: McArdles diseaseSystem Organ Class: 10010331 - Congenital, familial and genetic disordersMedDRA version: 19.0Level: LLTClassification code 10026969Term: McArdle's diseaseSystem Organ Class: 10010331 - Congenital, familial and genetic disordersMedDRA version: 19.0Level: PTClassification code 10018462Term: Glycogen storage disease type VSystem Organ Class: 10010331 - Congenital, familial and genetic disordersEUCTR2014-003644-12-DKeuromuscular Research Unit, Rigshospitalet28
已完成
2 期
Study of Triheptanoin for Treatment of Long-Chain Fatty Acid Oxidation DisorderVery Long-chain acylCoA Dehydrogenase (VLCAD) DeficiencyCarnitine Palmitoyltransferase 2 (CPT2) DeficiencyMitochondrial Trifunctional Protein (TFP) DeficiencyLong-chain 3 hydroxyacylCoA Dehydrogenase (LCHAD) DeficiencyNCT01379625Oregon Health and Science University32
已完成
2 期
A study to assess the long term retention on treatment and long-term safety and tolerability of Triheptanoin in male and female participants with drug-resistant epilepsyMedically refractory epilepsyNeurological - EpilepsyACTRN12615000406505niversity of Queensland12
进行中（未招募）
2 期
The n-3 fatty acid supplementation in breast tumor patientsRBR-2b2hqhniversidade de Brasília