Factors Affecting Medication Adherence to Topical Acne Medications: a Single-center, Prospective Study Evaluating the Adherence and Patient Satisfaction to Single and Multiple Topical Acne Medications
试验速览
- 阶段
- 早期 1 期
- 状态
- 进行中（未招募）
- 入组人数
- 72
- 试验地点
- 1
- 主要终点
- Medication Adherence
研究概览
简要总结
Acne is a chronic condition that typically requires the use of multiple medications.1 Medication adherence is especially challenging for patients with chronic diseases and often decreases over time, especially for those using topical medications.1 Nonadherence can result in multiple negative effects including treatment failure, increased healthcare costs, and decreased quality of life. Primary nonadherence refers to problems acquiring and starting treatment. Challenges to this form of nonadherence include a lack of knowledge, misunderstanding of usage, poor communication with provider, increased cost, and fear of side effects.2 Secondary nonadherence refers to when the patient does not use the medication as prescribed. Hurdles to secondary nonadherence include delayed results, increased complexity of treatment plan, adverse effects, busy lifestyle, and inconvenience.2
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adult patients ≥18 years of age
- •Patients with a current diagnosis of acne
- •Patients who live in the US,
- •Patients have sufficient command of the English language
排除标准
- •Patients less than the age of 18
- •Patients without a current diagnosis of acne
- •Patients who do not live in the US
- •Patients without a sufficient command of the English language
研究组 & 干预措施
One single fixed-combination product
Participants instructed to apply clindamycin phosphate 1.2%/adapalene 0.15%/BPO 3.1% gel once daily
干预措施: clindamycin phosphate 1.2%/adapalene 0.15%/BPO 3.1% gel (Drug)
Two products
Participants instructed to apply 0.3%/BPO 2.5% gel and compounded clindamycin phosphate 1.2% gel once daily
干预措施: adapalene 0.3%/BPO 2.5% gel and compounded clindamycin phosphate 1.2% gel (Drug)
Three products
Participants instructed to apply BPO 2.5% gel, adapalene 0.1% gel, and compounded clindamycin phosphate 1.2% gel once daily
干预措施: Compounded BPO 2.5% gel, adapalene 0.1% gel, and compounded clindamycin phosphate 1.2% gel (Drug)
结局指标
主要结局
Medication Adherence
时间窗: End of study visit - day 56
Medication adherence measured by the data from the electronic monitors by frequency of use recorded by number of times opened
次要结局
- Gender specific adherence (female subjects)(End of study visit - day 56)
- Gender specific adherence (male subjects)(End of study visit - day 56)