Use of Hypertonic Versus Isotonic Solutions in Off Pump Coronary Artery Bypass Graft Surgery Targeting the Left Marginal Branch
试验速览
- 阶段
- 4 期
- 发起方
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- Use of vasoactive drugs in left marginal branch off pump CABG surgery
研究概览
简要总结
This is a comparison between Hypertonic versus isotonic solution in a double blind randomized trial for off pump Coronary Artery Bypass Graft (CABG) surgery targeting the left marginal branch.
Hypertonic solution should provide better tolerance for heart mobilization with less volume expansion and less drugs.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Off pump CABG targeting the left marginal branch
排除标准
- •On pump surgery
研究组 & 干预措施
Hypertonic
Use of Hypertonic solution during left marginal branch CABG surgery.
干预措施: Hypertonic solution (Drug)
Isotonic
Use of Isotonic solution during left marginal branch CABG surgery.
干预措施: Isotonic (Drug)
结局指标
主要结局
Use of vasoactive drugs in left marginal branch off pump CABG surgery
时间窗: time related to left branch coronary anastomosis for drug need.
Comparison between hypertonic and isotonic solutions for need of vasoactive drugs with heart mobilization during left marginal branch off pump CABG surgery. Data will be collected respectively at 1, 5 and 10 minutes after beggining the left branch coronary anastomosis. Data will be type of drug need and dosage until the end os the anastomosis.
次要结局
- Fluid balance(Operative period and first operative day)
研究者
Roberto Rocha e Silva
Chief, Adult Heart Surgery, MD PHD in Cardiovascular Surgery
Hospital Pitangueiras