NCT02275013已完成不适用
Levosimendan Administration and Outcome in Cardiac Surgery
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 159
- 试验地点
- 1
- 主要终点
- In-hospital mortality
研究概览
简要总结
To assess the effects on outcome of levosimendan with respect to timing of its administration on the postoperative course of high-risk cardiac surgery patients in a retrospective observational study.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients undergoing cardiac surgery between 2006 and 2013
- •levosimendan administration within 24 hours of postoperative ICU admission
排除标准
- •patients younger than 18
研究组 & 干预措施
Early
Levosimendan administration within first hour of post-operative ICU admission
干预措施: Levosimendan (Drug)
Late
Levosimendan administration within 24 hours of post-operative ICU admission but after first hour
干预措施: Levosimendan (Drug)
结局指标
主要结局
In-hospital mortality
时间窗: until discharge, an average of 3 weeks length of stay
1 year follow-up mortality
时间窗: 1 year after surgery
次要结局
- Duration of mechanical ventilation(until discharge, an average of 3 weeks length of stay)
- Incidence of renal dysfunction(until discharge, an average of 3 weeks length of stay)
- Incidence of renal replacement therapy(until discharge, an average of 3 weeks length of stay)
研究者
Michael Sander
Univ-Prof. Dr. med.
Charite University, Berlin, Germany
研究点 (1)
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