clinical and etiological profile of acute kidney injury in patients admitted to intensive care units
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 400
- 试验地点
- 1
- 主要终点
- clinical profile of patients with acute kidney injury in ICU patients
研究概览
简要总结
Need for study
acute kidney injury incidence corresponds to almost 50%of all cause ICU admissions. AKI can be transient , persistent or acute kidney disease . there are still research gaps in the various causes and outcome of various causes of acute kidney injury , especially in developing countries , as the causes are different in both developing and developed countries . AKI reversal is observed in 72.9%of all AKI patients .
the risk of in hospital mortality , and ICU mortality increases with increased in lactate albumin ratio according to a study. Patients with higher lactate albumin ratio showed significant shorter survival time .
Description
patients are selected from ICU after they meet selection criteria for study . after taking written consent from the patient , data is collected including demographic profile, clinical symptoms , comorbidities , biochemical and etiological profile of the patient are collected as part of the study . laboratory data is collected . initial serum lactate and serum albumin values were taken from within 48 hrs of admission duration of stay was noted. the treatment information including hemodialysis .
data is analysed , lactate albumin ratio is calculated and analysed . patients are divided into 4 quartiles . mortality rates in relation to each quartile are analysed . patients are followed up till discharge and status at discharge noted. dialysis dependence is analysed . data is analysed using appropriate stastical methods used for analysis .
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 99.00 Year(s)(—)
- 性别
- All
入选标准
- •Patients admitted to icu with acute kindey injury.
排除标准
- •1.18years of age 2.Chronic kidney disease with end stage renal disease 3.Pregnancy 4.Chronic liver disease patients 5.Those on metformin 5.Malignancy.
结局指标
主要结局
clinical profile of patients with acute kidney injury in ICU patients
时间窗: at time of discharge
次要结局
- -to accesses lactate albumin ratio in predicting mortality of patient(-dialysis dependence analyzed)
