NL-OMON37801已完成4 期
Cross-sectional study of 24-hours blood pressure measures and left ventricular mass using echocardiograms in late adolescents and adults with ADHD. - ADDUCE: blood pressure and left ventrikel mass in ADHD.
niversitair Medisch Centrum Sint Radboud0 个研究点目标入组 320 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 320
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational invasive
入排标准
- 年龄范围
- 12 至 99（—）
入选标准
- •Target group:
- •Patients with ADHD according to DSM-IV criteria (any subtype), based on clinical diagnosis, and confirmed by a structured interview [depending on local procedures: ADHD module of the K-SADS (Kaufman et al., 2000) or CAADID (Conners Adult ADHD Diagnostic Interview for DSM-IV) (www.mhs.com/) or DIVA (Diagnostic Interview for Adult ADHD) (www.divacenter.eu/Content/Downloads/DIVA_2.pdf).
- •Aged between 15 and 25 years.
- •Any comorbidity is allowed.
- •Any comedication is allowed.
- •Treated with methylphenidate (IR or ER preparations) for 3 years or longer, continuously.;Note: we will attempt to recruit at least 50% of the participants of the target group being treated continuously for 3 years with a minimum effective dose of 0.5 mg methylphenidate /kg/day). Being treated continuously means being prescribed methylphenidate continuously but may include the presence of drug holidays. We will measure adherence by asking questions about drug holidays and % of the overall dose taken. We will allow for some variation in dosages prescribed to be able to analyze dose-response relationships.;Control group:
- •Patients with ADHD according to DSM*IV criteria (any subtype), based on clinical diagnosis.
- •Aged between 15 and 25 years.
- •Any comorbidity is allowed.
- •Any comedication is allowed.
- •Never been treated with methylphenidate.
排除标准
- •All Groups: Treatment with dexamfetamine or atomoxetine.
- •ADHD controls: Treatment with methylphenidate.
研究者
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