Outcomes of Early Laparoscopic Cholecystectomy in Cases of Acute Cholecystitis
试验速览
- 阶段
- 不适用
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- duration of surgery ,
研究概览
简要总结
Laparoscopic cholecystectomy is the most common laparoscopic surgery performed in the world. The initial treatment of acute calculus cholecystitis includes GIT rest, intravenous fluid, correction of electrolyte imbalance from repeated vomiting, good analgesia, and intravenous antibiotics. Following this treatment, patients with uncomplicated disease are managed on outpatient basis and are called for elective laparoscopic cholecystectomy after a period of 6-8 weeks.
Elective laparoscopic cholecystectomy has become the gold standard for treatment of symptomatic gallstones. However, in the early days, acute cholecystitis was a contraindication of laparoscopic cholecystectomy, and patients with acute cholecystitis were managed conservatively and discharged for re-admission in order to have elective surgery performed for the definitive treatment.
Early laparoscopic cholecystectomy, within 72 hours of presentation,has been advocated because of shorter hospital stay, decreased financial costs and reduced readmission rates. Previously cited reasons against early laparoscopic cholecystectomy include the increased technical difficulties, increased risk of conversion to an open procedure (6-35 % in some studies) and increased risks of biliary complications such as bile leaks and common bile duct (CBD) injuries when operating on an inflamed gallbladder with edematous planes and distorted anatomy.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 20 Years 至 70 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Any patient presented by Acute cholecystitis fit for lap cholecystectomy .
排除标准
- •Patients unfit for laparoscopic surgery such as patients with significant medical illness (ASAgrade more 3), pancreatitis and common bile duct stones
结局指标
主要结局
duration of surgery ,
时间窗: Intraoperative
compare between duration of surgery between traditional elective laparoscopic cholecystectomy and early laparoscopic cholecystectomy
percentage of complications
时间窗: 6 months
compare between percentage of complications of surgery between traditional elective laparoscopic cholecystectomy and early laparoscopic cholecystectomy
morbidity
时间窗: 6 months
compare morbidity between traditional elective laparoscopic cholecystectomy and early laparoscopic cholecystectomy
mortality
时间窗: 6 months
compare mortality between traditional elective laparoscopic cholecystectomy and early laparoscopic cholecystectomy
次要结局
未报告次要终点
研究者
Sherif Ali Ahmed
resident doctor at general surgery department at sohag university
Sohag University
