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临床试验/NCT05484232
NCT05484232Unknown不适用

Outcomes of Early Laparoscopic Cholecystectomy in Cases of Acute Cholecystitis

Sohag University1 个研究点 分布在 1 个国家目标入组 50 人开始时间: 2022年8月最近更新:
适应症

试验速览

阶段
不适用
入组人数
50
试验地点
1
主要终点
duration of surgery ,

研究概览

简要总结

Laparoscopic cholecystectomy is the most common laparoscopic surgery performed in the world. The initial treatment of acute calculus cholecystitis includes GIT rest, intravenous fluid, correction of electrolyte imbalance from repeated vomiting, good analgesia, and intravenous antibiotics. Following this treatment, patients with uncomplicated disease are managed on outpatient basis and are called for elective laparoscopic cholecystectomy after a period of 6-8 weeks.

Elective laparoscopic cholecystectomy has become the gold standard for treatment of symptomatic gallstones. However, in the early days, acute cholecystitis was a contraindication of laparoscopic cholecystectomy, and patients with acute cholecystitis were managed conservatively and discharged for re-admission in order to have elective surgery performed for the definitive treatment.

Early laparoscopic cholecystectomy, within 72 hours of presentation,has been advocated because of shorter hospital stay, decreased financial costs and reduced readmission rates. Previously cited reasons against early laparoscopic cholecystectomy include the increased technical difficulties, increased risk of conversion to an open procedure (6-35 % in some studies) and increased risks of biliary complications such as bile leaks and common bile duct (CBD) injuries when operating on an inflamed gallbladder with edematous planes and distorted anatomy.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Single Group
主要目的
Treatment
盲法
None

入排标准

年龄范围
20 Years 至 70 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Any patient presented by Acute cholecystitis fit for lap cholecystectomy .

排除标准

  • Patients unfit for laparoscopic surgery such as patients with significant medical illness (ASAgrade more 3), pancreatitis and common bile duct stones

结局指标

主要结局

duration of surgery ,

时间窗: Intraoperative

compare between duration of surgery between traditional elective laparoscopic cholecystectomy and early laparoscopic cholecystectomy

percentage of complications

时间窗: 6 months

compare between percentage of complications of surgery between traditional elective laparoscopic cholecystectomy and early laparoscopic cholecystectomy

morbidity

时间窗: 6 months

compare morbidity between traditional elective laparoscopic cholecystectomy and early laparoscopic cholecystectomy

mortality

时间窗: 6 months

compare mortality between traditional elective laparoscopic cholecystectomy and early laparoscopic cholecystectomy

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Sherif Ali Ahmed

resident doctor at general surgery department at sohag university

Sohag University

研究点 (1)

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