NCT05196425已完成不适用
Expression of PARP-1 in Optic Neuritis of Multiple Sclerosis Patients
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 80
- 试验地点
- 2
- 主要终点
- measure PARP-1 mRNA
研究概览
简要总结
This study will explore the expression of PARP-1 in optic neuritis of multiple sclerosis patients.
The data will be collected from Sohag University hospital in the period from the start of August 2021 to the end of December 2021.
The study protocol will be approved by the Scientific Research Ethical Committee, Faculty of Medicine, Sohag University.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Diagnostic
- 盲法
- Single (Investigator)
入排标准
- 年龄范围
- 20 Years 至 45 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patients with multiple sclerosis with or without optic neuritis Multiple sclerosis will be diagnosed according to the McDonald criteria
排除标准
- •• Isolated optic neuritis.
结局指标
主要结局
measure PARP-1 mRNA
时间窗: 2 weeks
measure PARP-1 mRNA
次要结局
- Optic nerve, RNFL and GCC layer affection by MS(2 weeks)
研究者
Elshimaa A.Mateen
Lecturer of ophthalmology
Sohag University
研究点 (2)
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