NCT01249053Unknown不适用
Expression of Optic Atrophy Type 1 (OPA1) Protein in Lung Adenocarcinoma
适应症
试验速览
- 阶段
- 不适用
- 入组人数
- 100
- 试验地点
- 1
研究概览
简要总结
Optic atrophy type 1(OPA1) is a nuclear dynamin-related GTPase, targeted to the inner mitochondrial membrane, which plays a role in mitochondrial fusion. Mitochondria fusion is associated with process of apoptosis. . OPA1 plays an important role in the mitochondrial bioenergetics and mitochondrial networks. The changes in mitochondrial shape and mitochondrial bioenergetics may be cause of the disease. In this study, we investigate the expression of OPA1 in lung adenocarcinoma (LADC) cells and tissue.
研究设计
- 研究类型
- Observational
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 25 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •We will collect paraffin blocked resected lung tissue samples from stage I~IIIa non-small cell lung cancer patients (age, 40~80 years old) who received lobectomy of the affected lung.
排除标准
- •History of uremia, other malignant disease, and liver cirrhosis
- •History of pneumonia and pulmonary tuberculosis
- •History of long period of medications.
研究者
研究点 (1)
Loading locations...
相似试验
招募中
2 期
Tolerance and Efficacy Nicotinamide (vitamin B3) in Dominant Optic Atrophy OPA1Nicotinamide Adverse ReactionNCT06007391University Hospital, Angers25
已完成
不适用
Expression of PARP-1 in Multiple Sclerosis PatientsMultiple SclerosisNCT05196425Sohag University80
已完成
不适用
How Does Your Genetic Make-up (Profile) Influence Your Glaucoma?Primary Open Angle GlaucomaNCT00626847Wills Eye97
已完成
不适用
Mitochondria and Metabolic Syndrome in a Southern California Chinese CohortMetabolic SyndromeType 2 Diabetes MellitusNCT00786721University of California, Irvine9
招募中
不适用
Metabolomics Analysis According to the Retinal Nerve Fiber Layer in Patients With NOHL Mutations (MétabOCT)Healthy SubjectsLeber Hereditary Optic NeuropathyNCT06682819Hôpital Necker-Enfants Malades90