Study Of Immediate Induction Of Labor With Cerviprime gel and Delayed Induction Of Labor With Oxytocin at Term Prelabor Rupture Of Membranes

·         Antenatal women at term with prelabor rupture of membranes with amniotic fluid leak from cervical os is confirmed  by sterile per speculum examination under aseptic conditions are included in study after taking history and written informed consent.

·         Prophylactic antibiotics will be administered and nonstress test will be performed to know fetal wellbeing.

·         Amount of liquor will be assessed by ultrasonography.

·         The antenatal women who are not in labor are  divided into two groups by Modified bishop’s score. Patients who are fulfilling inclusion criteria are selected and seggregated into two groups after counselling, based on their will.

·         In group A, they will be induced immediately within 6hours of prelabor rupture of membranes with intravaginal instillation of 0.5mg Prostaglandin E2 gel into posterior fornix. If bishop’s score doesnot improve after 6hours then application of  Prostaglandin E2 gel is repeated maximum of two doses. After two doses of Prostaglandin E2 gel, labor augmentation will be done with oxytocin.

·         In group B, the patients included are those with prelabor rupture of membranes with duration morethan or equal to 6 hours. They will be observed for 12hours for spontaneous onset of labor, if patient fails then induction or augmentation with intravenous oxytocin drip is started, 5U in 500ml ringer lactate solution in primigravida and 2.5U in 500ml ringer lactate solution in multiparous women with infusion rate of 4 drops per min. The rate of infusion is doubled every 20mins until the occurrence of  4 contractions lasting for 45 seconds in 10mins, upto maximum infusion rate of 32mIU/min.

·         Both groups are closely monitored by:

Temperature recording 4th hourly.

Maternal tachycardia.

Uterine contractions.

Fetal heartrate auscultation every 30mins.