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临床试验/NCT07086092
NCT07086092已完成不适用

Relationship Between Serum Markers and Motor Recovery and Ambulation in Post-stroke Patients: a Retrospective Analysis

Abant Izzet Baysal University1 个研究点 分布在 1 个国家目标入组 257 人开始时间: 2025年7月15日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
257
试验地点
1
主要终点
Serum magnesium levels

研究概览

简要总结

This study aim to retrospectively investigate the effects of the magnesium, vitamin D, and uric acid serum markers on motor recovery and ambulation in post-stroke patients.

详细描述

Stroke is the sudden loss of neurological function associated with a reduction or cessation of blood flow in the brain, resulting from the blockage or rupture of cerebral vessels. Stroke is the second leading cause of death and the third leading cause of disability worldwide. Regaining motor recovery and ambulation skills in patients is one of the main goals of rehabilitation. It is critical for patients to improve their quality of life and regain their independence. Serum biochemical markers can be used to predict post-stroke recovery. Serum magnesium, vitamin D, and uric acid are biochemical markers that may play a role in the recovery process of stroke patients.

This study aim to retrospectively investigate the effects of the magnesium, vitamin D, and uric acid serum markers on motor recovery and ambulation in post-stroke patients.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

年龄范围
30 Years 至 90 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Patients who had a single stroke between 2019 and 2024
  • Patients who were admitted to the rehabilitation ward and had their serum vitamin D, magnesium, and uric acid levels measured
  • Patients whose functional ambulation scale scores and Brunnstrom motor recovery stages were recorded

排除标准

  • Patients with other neurological diseases
  • Patients with multiple strokes
  • Patients with gout, renal failure, or hyperparathyroidism

结局指标

主要结局

Serum magnesium levels

时间窗: Before treatment

Serum magnesium levels measured before the patients' rehabilitation will be obtained from past medical records.

Serum uric acid levels

时间窗: Before treatment

Serum uric acid levels measured before the patients' rehabilitation will be obtained from past medical records.

Serum vitamin D levels

时间窗: Before treatment

Serum vitamin D levels measured before the patients' rehabilitation will be obtained from past medical records.

Brunnstrom Motor Recovery Stage

时间窗: Before treatment

Brunnstrom stages is a scale used to assess motor recovery after a stroke, which is expressed using values between 1 and 6. The higher the value on this scale, the higher would be the recovery. Brunnstrom Motor Recovery Stages measured before the patients' rehabilitation will be obtained from past medical records.

Functional Ambulation Classification

时间窗: Before treatment

Functional Ambulation Classification is a 6-point functional walking test that evaluates ambulation ability and determines the amount of human support required by patients while walking, regardless of whether they use a personal assistive device. A score of 0 indicates that the patient has a dysfunctional ambulation A score of 5 denotes independent ambulation on any surface. Functional Ambulation Classification Stages measured before the patients' rehabilitation will be obtained from past medical records.

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Serdar Kilinc

assistant professor

Abant Izzet Baysal University

研究点 (1)

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