A Randomized Controlled Trial to evaluate the efficacy of Tejovatyadi Gutika Mukha-Dharan and Khadiradi Gutika Mukha-Dharan in Galagraha.
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 66
- 试验地点
- 1
- 主要终点
- Symptoms like Kantha-shopha (Oedema of Oro-pharynx), Kantha-kandu (Itching in Oro-pharynx), Aaraktata (Congestion of posterior pharyngeal wall) will be decreased
研究概览
简要总结
Galagraha described in Ayurveda is a throat disorder characterized by pain, irritation, inflammation, and difficulty in swallowing, which clinically resembles acute pharyngitis. Mukha-Dharan (holding medicated formulations in the oral cavity) is an important local therapeutic procedure used in the management of throat diseases. Tejovatyadi Gutika and Khadiradi Gutika are classical Ayurvedic formulations known for their anti-inflammatory, antimicrobial, and soothing properties and are commonly used in throat disorders.
The present study is planned as a randomized controlled clinical trial to evaluate and compare the efficacy of Tejovatyadi Gutika Mukha-Dharan and Khadiradi Gutika Mukha-Dharan in the management of Galagraha. Patients fulfilling the diagnostic criteria will be randomly divided into two groups and treated with the respective interventions. Clinical parameters such as throat pain, dysphagia, irritation, and congestion will be assessed before and after treatment. The results will be analyzed statistically to determine the effectiveness of both therapies and their comparative efficacy in relieving the symptoms of Galagraha.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- None
入排标准
- 年龄范围
- 19.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients of age group 19 to 60 years, irrespective of their gender, religion, occupation and socio-economic status.
- •All patients having signs and symptoms of Galagraha as follows i.
- •Kantha-shopha (Oedema of Oro-pharynx) ii.
- •Kantha-kandu (Itching in Oro-pharynx) iii.
- •Aaraktata (Congestion of posterior pharyngeal wall).
排除标准
- •Patients having moderate to high grade fever, having body temperature of greater than 100F.
- •Patients suffering from complications like para-tonsillar abscess (quinsy), parapharyngeal abscess and other deep neck space infections.
- •Patients diagnosed with malignancies of pharynx and oral cavity or systemic illness like Tuberculosis and other lower respiratory tract infections.
结局指标
主要结局
Symptoms like Kantha-shopha (Oedema of Oro-pharynx), Kantha-kandu (Itching in Oro-pharynx), Aaraktata (Congestion of posterior pharyngeal wall) will be decreased
时间窗: Follow up on 3rd and 7th day. Observational follow up on 14th day.
次要结局
未报告次要终点
研究者
Dr Piyush Manoj Aloni
MAMs Sumatibhai Shah Ayurved Mahavidyalaya