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临床试验/NCT07008534
NCT07008534尚未招募不适用

Evaluation of Neurosensory Function of Inferior Alveolar Nerve Following Lateralization With Sticky Bone Versus Nil Using Computer Guided Dental Implant Placement: A Randomized Clinical Trial

Cairo University0 个研究点目标入组 18 人开始时间: 2025年7月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
尚未招募
入组人数
18
主要终点
Clinical neurosensory assessment of inferior alveolar nerve.

研究概览

简要总结

The aim of this study is to evaluate the effect of sticky bone on acceleration of recovery of the neurosensory dysfunction of the inferior alveolar nerve following inferior alveolar nerve lateralization surgery for implant placement in patients with posterior vertical bone deficiency in order to overcome the main disadvantage of this technique & provide a reliable,saving time - computer guided simultaneous implant placement- and improved technique.

详细描述

Lateralization of IAN allows simultaneous implant placement with longer implants and primary stability.2 IAN lateralization provides an option to avoid costly, prolonged bone graftt and also healing periods can be reduced by this option of treatment Vestibular depth remains intact as there is no augmentation in the underlying bone defect. 2 IAN lateralization technique has also some advantages such as less morbidity and less of peri-implant disease.2 In case of the IAN is located in the superior part of the body of the mandible , and presence of mild atrophy of the edentulous alveolar ridge will fetch the alveolar ridge in a close relation to the neuro-vascular bundle, The incidence of "high" IAN locations ranges from 14.6 to 30.7%. 1However there is some complications such as numbness after surgery which is considered as the most common one also prevent thermal conductivity via implants(Kahnberg et al., 2000) so sticky bone is going to be used to act as an insulator between dental imlants & Inferior alveolar nerve and it contains a number of growth factors so it is predicted to play an important role to enhance recovery of the inferior alveolar nerve after surgery

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Triple (Participant, Investigator, Outcomes Assessor)

入排标准

性别
All
接受健康志愿者
是

入选标准

  • •Adult patients requiring oral rehabilitation with dental implants in vertically atrophied
  • •Posterior mandibular region, less than 8mm of bone above the mandibular canal.
  • •Patients should be free from any systemic conditions that may affect normal healing.
  • •Absence of any pathological conditions involving mandibular bones.

排除标准

  • •Patients under bisphosphonates treatment.
  • •Any contraindication for general anaesthesia.
  • •Osteoporotic patients.
  • •Patients with neurological disorders (neuralgias, Parkinson' s disease).
  • •Patients with systematic disease that may complicate healing.

研究组 & 干预措施

Computer guided immediate implant placement & IAN lateralization

Active Comparator

Patients receiving computer-guided immediate implant placement and inferior alveolar nerve (IAN) lateralization only.

干预措施: Patients receiving computer-guided immediate implant placement and inferior alveolar nerve (IAN) lateralization only. (Procedure)

computer guided immediate implant placement & IAN lateralization with Sticky bone

Experimental

Patients receiving computer-guided immediate implant placement and inferior alveolar nerve (IAN) lateralization with sticky bone

干预措施: IAN lateralization with computer-guided immediate implant placement using Sticky Bone (Procedure)

结局指标

主要结局

Clinical neurosensory assessment of inferior alveolar nerve.

时间窗: 6 months

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Muhammad Ashraf Elsawi

Resident

Cairo University

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