Correlation Between B Regulatory Cell and Vitamin D Status in Term and Preterm Labor
试验速览
- 阶段
- 不适用
- 入组人数
- 90
- 试验地点
- 1
- 主要终点
- Changes in number of B regulatory cell in pregnant woman
研究概览
简要总结
During pregnancy , the maternal immune system is always confronted with fetal alloantigens. the immunological mechanisms that prevent the rejection of the fetus are still not under understood.
详细描述
During pregnancy , the maternal immune system is always confronted with fetal alloantigens. the immunological mechanisms that prevent the rejection of the fetus are still not under understood.the fetus is normally accepted by the maternal immune system despite despite the expression of paternal alloantigens. Normally, the fetus grows and develops very well with ongoing pregnancy.
B regulatory cells are increased in pregnant women compared to non-pregnant women.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 20 Years 至 50 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •healthy female according to the required groups
排除标准
- •patient with infectious disease , tuberculosis ,tumor ,hematologic disease,metabolic bone disease or any other connective tissue diseases were excluded.
- •Patient with viral hepatitis.
- •serological evidence of HIV infection.
结局指标
主要结局
Changes in number of B regulatory cell in pregnant woman
时间窗: 9 months
Immune system immunosuppressed to maintain fetus
次要结局
未报告次要终点
研究者
Haitham Mohamed Sedky
Principle investigator
Assiut University