Drinking water to dilute urine osmolality is associated with greater weight loss than drinking water following thirst in overweight pre-adolescents eating lower glycemic foods: A completer?s analysis of a controlled trial

Children's Hospital Oakland Research Institute (USA)0 个研究点目标入组 30 人开始时间: 2013年1月18日最近更新: 2015年1月13日

适应症

试验速览

暂无简介。

•1. All participants were screened for a body mass index (BMI) above the 85th percentile for age and sex
•2. Motivation to lose weight
•3. Daily intake of caloric beverages, including juice, soda, milks, and/or sports drinks, less than 2L per day drinking water
•4. Willingness to adopt food and beverage changes
•5. Boys and girls, at any stage of puberty
•6. Who spoke English or Spanish

•1. Any health condition that could make study participation harmful
•2. Acute illness
•3. A fluid balance disorder
•4. Any chronic condition or medication that stimulates vasopressin release, or any condition for which venipuncture is counter indicated.
•5. Potential participants were also excluded if they had any condition or medication known to promote weight gain.
•6. Specific exclusion criteria included:
•6.1. Renal disease (previous diagnosis, +3 proteinuria dipstick test, frequent urination)
•6.2. Congestive heart failure
•6.3. Adrenal insufficiency
•6.4. Syndrome of inappropriate secretion of antidiuretic hormone (SIADH)
•6.5. Chronic pain
•6.6. Psychogenic polydipsia
•6.7. Bleeding disorders
•6.8. Hemophila
•6.9. Recent cancer chemotherapy
•6.10. Syndromic conditions (e.g. Prader-Willi, Bardet-Biedl)
•6.11. Weight loss pharmacotherapy
•6.12. Anti-depressent, anti-psychotic or lipid-lowering medications, adrenergic or cholinergic drugs, clofibrate, chlorpropamide, carbamazepine, phenothiazines, vincristine, cyclophosphamide, morphine barbiturates, opiates, and glucocorticoid therapy in excess of physiologic dosing (i.e. > 15 mg/m2/d).
•7. Persons who had lost weight in the previous 2 months were excluded
•8. Persons who expressed aversion to drinking water or the prescribed study foods, or who had plans to move to a new address during the study period were also excluded from the study

发起方

Children's Hospital Oakland Research Institute (USA)