跳至主要内容
临床试验/NCT04315662
NCT04315662Unknown不适用

Effects of a Power Training at Two Different Loads on Muscle Quality and Functional Capacity in Women Aged 65-75.

Universidad del Valle, Colombia1 个研究点 分布在 1 个国家目标入组 56 人开始时间: 2020年5月1日最近更新:
适应症

试验速览

阶段
不适用
发起方
入组人数
56
试验地点
1
主要终点
Change on muscle quality: obtained by measuring mean leg extension power divided by muscle mass of thighs

研究概览

简要总结

Muscle power training has proven to be an effective intervention to prevent sarcopenia and frailty in old people. In the last decade, new concepts related to the functionality of old people have been generated, such as muscle quality and functional capacity.

The power training consists of rapid movements of short duration that imply a more specialized neuromuscular response and that improve the functional response reflected in activities of daily life that demand a certain manifestation of muscular power (stand up of a chair, climbing stairs, rebalance, accelerate suddenly, among others). Therefore, it is important to investigate the dose-response relationships in power training in older people and establish how possible improvements in muscle quality can be reflected in functional capacity.

The aim of this study is to compare the effects of power training at two different loads on muscle quality and functional capacity in women aged 65-75

详细描述

Fifty-six women will be randomly assigned to one of two muscle power training supervised for a physical activity instructor with different velocity loss (VL) thresholds: 10% (VL10) and 30% (VL30). Subjects followed a muscle power training for 8 weeks (2 sessions per week on alternate days) using the leg extension exercise, with similar relative intensity (50% 1RM). Between weeks one and four two series will be performed per session. Then the number of series will increase to three per session. The inter-set recovery period will be always of 2-min.

Before and after the muscle power training the following tests will be performed: 1) measure of body composition with dual-energy x-ray absorptiometry for determining the lean mass of thighs; 2) three functional test (chair stand test, time up go test with cognitive task and gait speed test); 3)Progressive loading test in a leg extension machine until finding the mean muscle power corresponding to 50% of 1RM (speed of concentric phase of 6.67 ± 0.04 m/s measured using a camera-based optoelectronic system).

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Single (Outcomes Assessor)

入排标准

年龄范围
65 Years 至 75 Years(Older Adult)
性别
Female
接受健康志愿者

入选标准

  • Women 65 to 75 years.
  • Healthy volunteers.
  • Have not perform muscle power training in the last six months.

排除标准

  • History of asthma.
  • History of uncontrolled diabetes.
  • History of uncontrolled hypertension.
  • History of cardiovascular disease.
  • History of coronary heart disease.
  • Arrhythmias.
  • Personal history of surgical procedures in the last three months.
  • Uncontrolled non-communicable diseases.
  • Psychological, sensitive, cognitive, neuromotor and/or osteo-muscular conditions that may affect participation in an exercise program.
  • Under medical treatment with anticoagulants, bronchodilators, and/or steroids.

结局指标

主要结局

Change on muscle quality: obtained by measuring mean leg extension power divided by muscle mass of thighs

时间窗: Baseline and after 8 weeks

The muscle quality will be obtained by measuring mean leg extension power divided by muscle mass of thighs (measured by dual-energy x-ray absorptiometry)

次要结局

  • Change on gait speed test(Baseline and after 8 weeks)
  • Change on time up go test with cognitive task(Baseline and after 8 weeks)
  • Change on chair stand test(Baseline and after 8 weeks)

研究者

发起方
Universidad del Valle, Colombia
申办方类型
Other
责任方
Sponsor

研究点 (1)

Loading locations...

相似试验