Effects of Eccentric-based Training on Muscle Strength and Physical Function in Older Adults
试验速览
- 阶段
- 不适用
- 入组人数
- 27
- 试验地点
- 2
- 主要终点
- Gait speed
研究概览
简要总结
Sarcopenia leads to loss of muscle mass and muscle strength during the aging process. It has been reported that eccentric training has some positive effects on the preservation of eccentric strength, with less delayed onset muscle soreness (DOMS) in older groups, and lower metabolic costs.
详细描述
This is prospective study. The goals of this study are to:
- Examine the effects of eccentric training on physical function (gait speed, stair climb, chair stand) in older adults.
- Examine the effects of eccentric training on muscle strength (Isometric strength, Isokinetic strength, power) in older adults.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- Triple (Participant, Care Provider, Outcomes Assessor)
入排标准
- 年龄范围
- 60 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Subjects who can agree voluntarily
- •Older men/women: Age (60 - 80 yrs)
排除标准
- •Uncontrolled hypertension
- •Acute coronary syndrome
- •Subjects who took drugs which can affects neuromuscular system
- •Subjects who cannot agree voluntarily
研究组 & 干预措施
Older adults
Older adults (Over the 60 years), Subjects did not suffer from musculoskeletal or metabolic diseases.
干预措施: Eccentric exercise (Device)
Older adults-Control
Older adults (Over the 60 years), Subjects did not suffer from musculoskeletal or metabolic diseases.
干预措施: Conventional resistance exercise (Device)
No intervention
Metabolic diseases, Hypertension (150/90mmHg), Myocardial infarction within 6 months. Fractures within 6 months.
结局指标
主要结局
Gait speed
时间窗: Change from baseline gaitspeed at 8 weeks
An examiner used a stopwatch to time how long it took subjects to walk along a marked tape. The Kinect device was used to measure gait speed.
Stair climb
时间窗: Change from baseline stair climb at 8 weeks
Subjects were measured on eight 17-cm stairs twice, requiring a step by step pattern, where the timer activated when the first contact was made at the first step and ended when the contact occurred at the last step before and after the 8 weeks of exercise training.
Chair stand
时间窗: Change from baseline chair stand at 8 weeks
Subjects had to get up from a chair measuring 41 cm in height with a flat seat. Subjects were asked to stand up and sit down 5 times as quickly as possible with their arms folded across the chest. They stood up until full extension was observed at the trunk and lower limb joints, and returned to a seated position with their back fully supported at the back of the chair.
次要结局
- Isokinetic knee strength(Change from baseline isokinetic knee strength at 8 weeks)
- Isometric knee strength(Change from baseline isometric knee strength at 8 weeks)
- Power(Change from baseline power at 8 weeks)
研究者
Jae-Young Lim
Professor, Department of Rehabilitation Medicine
Seoul National University Bundang Hospital