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Clinical Trials/NCT04099316
NCT04099316
Unknown
Not Applicable

Effects of Eccentric-based Training on Muscle Strength and Physical Function in Older Adults

Seoul National University Bundang Hospital1 site in 1 country27 target enrollmentJuly 20, 2017
ConditionsSarcopenia

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Sarcopenia
Sponsor
Seoul National University Bundang Hospital
Enrollment
27
Locations
1
Primary Endpoint
Gait speed
Last Updated
6 years ago

Overview

Brief Summary

Sarcopenia leads to loss of muscle mass and muscle strength during the aging process. It has been reported that eccentric training has some positive effects on the preservation of eccentric strength, with less delayed onset muscle soreness (DOMS) in older groups, and lower metabolic costs.

Detailed Description

This is prospective study. The goals of this study are to: 1. Examine the effects of eccentric training on physical function (gait speed, stair climb, chair stand) in older adults. 2. Examine the effects of eccentric training on muscle strength (Isometric strength, Isokinetic strength, power) in older adults.

Registry
clinicaltrials.gov
Start Date
July 20, 2017
End Date
October 31, 2019
Last Updated
6 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Jae-Young Lim

Professor, Department of Rehabilitation Medicine

Seoul National University Bundang Hospital

Eligibility Criteria

Inclusion Criteria

  • Subjects who can agree voluntarily
  • Older men/women: Age (60 - 80 yrs)

Exclusion Criteria

  • Uncontrolled hypertension
  • Acute coronary syndrome
  • Subjects who took drugs which can affects neuromuscular system
  • Subjects who cannot agree voluntarily

Outcomes

Primary Outcomes

Gait speed

Time Frame: Change from baseline gaitspeed at 8 weeks

An examiner used a stopwatch to time how long it took subjects to walk along a marked tape. The Kinect device was used to measure gait speed.

Stair climb

Time Frame: Change from baseline stair climb at 8 weeks

Subjects were measured on eight 17-cm stairs twice, requiring a step by step pattern, where the timer activated when the first contact was made at the first step and ended when the contact occurred at the last step before and after the 8 weeks of exercise training.

Chair stand

Time Frame: Change from baseline chair stand at 8 weeks

Subjects had to get up from a chair measuring 41 cm in height with a flat seat. Subjects were asked to stand up and sit down 5 times as quickly as possible with their arms folded across the chest. They stood up until full extension was observed at the trunk and lower limb joints, and returned to a seated position with their back fully supported at the back of the chair.

Secondary Outcomes

  • Isokinetic knee strength(Change from baseline isokinetic knee strength at 8 weeks)
  • Isometric knee strength(Change from baseline isometric knee strength at 8 weeks)
  • Power(Change from baseline power at 8 weeks)

Study Sites (1)

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