NCT01653002已完成不适用
Methylation Level of SHOX2 in Endobronchial Ultrasound With Real-time Guided Transbronchial Needle Aspiration for Lung Cancer Staging
University Hospital, Essen1 个研究点 分布在 1 个国家目标入组 200 人开始时间: 2012年2月最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- Diagnostic Performance of SHOX2
研究概览
简要总结
A DNA hypermethylation of the gene locus SHOX2 can be frequently found in lung cancer tissue. The purpose of this study is to determine whether the assessment of the hypermethylation level of SHOX2 in specimens obtained by endosonographic guided bronchoscopy makes a contribution to lung cancer staging.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 90 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •clinical diagnosis of lung cancer
- •enlarged mediastinal or hilar lymph nodes (>10 mm)
排除标准
- •clinical condition which excludes general anesthesia
结局指标
主要结局
Diagnostic Performance of SHOX2
时间窗: one Year
Diagnostic performance of SHOX2 methylation Level as biomarker for lung cancer compared to histologic evaluation of EBUS-TBNA specimen alone.
次要结局
未报告次要终点
研究者
Kaid Darwiche
Dr. med. Kaid Darwiche
University Hospital, Essen
研究点 (1)
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