High-Flow Nasal Cannula for severe COVID-19, a multicentre prospective cohort study

o sponsors0 个研究点目标入组 600 人开始时间: 待定最近更新: 2024年2月28日

适应症

试验速览

暂无简介。

•The population included will be hospitalized patients with confirmed COVID-19, = 18 years old with isolated severe hypoxic respiratory failure defined as: SpO2 < 92% and/or BF>30/min despite treatment with at least 6 L/min oxygen therapy on nasal cannula. These patients may be included at the pulmonary departments delivering COVID-19 care, intensive care units or directly on the Emergency department. SARS-CoV-2 negative patients (nasopharyngeal PCR) will be excluded for this analysis, retrospectively.
•Inclusion criteria
•In order to be eligible to participate in this study, a subject must meet all of the following inclusion criteria:
•? Age = 18 years
•? Admitted to the hospital
•? Suspect of COVID-19 or nasopharyngeal swab PCR confirmed COVID-19
•? SpO2 < 92% and/ or breathing frequency >30/min despite at least 6L O2/min on nasal cannula.

•A potential subject who meets any of the following criteria will be excluded from participation in this study:
•? Reasons for direct intubation, as per local standard of clinical care.
•? Patient does not accept treatment with HFNC
•? Anatomic abnormalities (recent surgery of the face, nose, or airway) that preclude an appropriate-fitting nasal cannula

发起方

o sponsors