NL-OMON46515已完成不适用
Effects of wakame and spirulina consumption on intestinal cholesterol absorption in non-hypercholesterolemic men and women - Algae and cholesterol absorption
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 37
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 64（—）
入选标准
- •* Apparently healthy men and women;
- •* Aged between 18 and 70 years;
- •* BMI between 18 and 30 kg/m2
- •* Non-smoking;
- •* No elevated serum triacylglycerol concentrations (< 4.5 mmol/L);
- •* Willing to comply to the study protocol during the study;
- •* Agreeing to be informed about medically relevant personal test-results.
排除标准
- •* Not willing to abstain from any algae and/or seaweed consumption or algae/seaweed containing products (including sushi, see appendix I) two weeks before the start and during the trial;
- •* Use of plant-sterol/stanol-enriched foods (e.g. Becel Proactive) or supplements in the four weeks prior to the screening and/or during the study;
- •* Use of cholesterol or lipid-lowering medications (e.g. statins, bile-acid sequestrates, cholesterol absorption inhibitors);
- •* Use of any kind of medication or a medically prescribed diet, which can interfere with the study (judged by the principal investigator);
- •* Use of oral antibiotics in 40 days or less prior to the start of the study;
- •* Use of food supplements that might interfere with study measurements (judged by the principal investigator) in four weeks or less prior to the start of the study;
- •* Indications of treatment according to the Standard for Cardiovascular Risk Management from the Dutch General Practitioners community (NHG 2012);
- •* Any medical condition that might interfere with study (measurements), judged by the principal investigator, including cardiovascular diseases or events (e.g. acute myocardial infarction or cerebro-vascular accident), diabetes, asthma, COPD, rheumatoid arthritis, and gastro-intestinal diseases (e.g. inflammatory bowel disease);
- •* Unstable body weight (weight gain or loss > 3 kg in the past 3 months);
- •* Females who are pregnant, breast feeding or who may wish to become pregnant during the study;
- •* Consumption of > 14 (males) or > 10 (females) alcoholic consumptions a week;
- •* Reported intense sporting activities > 10 hours a week;
- •* Abuse of drugs;
- •* Participation in any other biomedical trial four weeks prior to the screening visit;
- •* Having donated >150 ml blood within 1 month prior to the screening visit, planning to donate blood during the study or within one month after finishing the study;
- •* Impossible or difficult to puncture as evidenced during the screening visit.
研究者
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